Results 161 to 170 of about 33,894 (216)

The malate–aspartate shuttle supports thermogenic lipid mobilization in brown adipocytes

The FEBS Journal, EarlyView.
Brown fat cells burn lipids within their mitochondria to generate heat. This process involves two energy “shuttles,” one of which is naturally blocked during heat production. We found that the second shuttle (MASh) is not required to generate heat. However, when MASh is disabled, the fatty acids meant for fuel are instead converted back into stored fat.
Michaela Veliova, Caroline M. Ferreira, Katrina P. Montales, Francisco Villalobos, Alexandra J. Brownstein, Rebeca Acín‐Pérez, Gabrielly S. Ferreira, Anthony E. Jones, Linsey Stiles, Ajit S. Divakaruni, Marc Liesa, Orian S. Shirihai, Marcus F. Oliveira   +12 more
wiley   +1 more source

Enhancing urban vehicular communication and safety through HMM-OCR. [PDF]

Sci Rep
Juvvalapalem S, Kanagaraj V.
europepmc   +1 more source

Brain tissue classification in hyperspectral images using multistage diffusion features and transformer

Journal of Microscopy, EarlyView.
Abstract Brain surgery is a widely practised and effective treatment for brain tumours, but accurately identifying and classifying tumour boundaries is crucial to maximise resection and avoid neurological complications. This precision in classification is essential for guiding surgical decisions and subsequent treatment planning.
Neetu Sigger, Tuan T. Nguyen, Gianluca Tozzi   +2 more
wiley   +1 more source

RENAsym, a quantitative systems toxicology platform model, designed to predict drug-induced kidney injury indicates polymyxin B and valproate overdose toxicity potential while simultaneously demonstrating acetaminophen and valproate safety at therapeutic levels. [PDF]

Toxicol Sci
Vallejo C, Bhargava P, Hamzavi N, McDaniel M, Lakhani VV, Qi T, Battista C, Clemens L, Shoda LKM, Kenz ZR, Tallapaka S, Gebremichael Y, Woodhead JL.   +12 more
europepmc   +1 more source

Uninformative news, limited attention and institutional investors

Journal of Risk and Insurance, EarlyView.
Abstract Using the universe of transaction‐level data in the U.S. corporate bond market around uninformative downgrades, we find an abnormal increase in trading volume, abnormal bond returns, and a subsequent reversal. On the contrary, we do not find a reversal for abnormal bond returns associated with informative rating actions.
Maria Efthymiou, Pingyi Lou, Andreas Milidonis   +2 more
wiley   +1 more source

Oculocardiac reflex during endoscopic brow lift: A case report. [PDF]

JPRAS Open
Tangchirakhaphan S.
europepmc   +1 more source

Metabolic Reprogramming and GM‐CSF Secretion in Areca Nut‐Activated Fibroblasts Drive Oral Precancer Progression

Oral Diseases, EarlyView.
ABSTRACT Objective Oral cancer, with a rising global incidence and poor prognosis, is associated with areca nut use in South and Southeast Asia. In this study, we addressed the effects of areca nut extract (ANE) on oral carcinogenesis by modulating fibroblast behavior in oral tissue.
Yen‐Yun Wang, Chang‐Wei Su, Chih‐Huang Tseng, Pang‐Yu Chen, Hieu D. H. Nguyen, Leong‐Perng Chan, Yuk‐Kwan Chen, Shih Sheng Jiang, Steven Lo, Shyng‐Shiou F. Yuan   +9 more
wiley   +1 more source

Sex differences in mitochondrial function in aging mouse skeletal muscle. [PDF]

Front Aging
Holcom A, Liao A, Holden KG, Bronikowski AM, Webb AE.   +4 more
europepmc   +1 more source

Porphyromonas gingivalis GroEL exacerbates orthotopic allograft transplantation vasculopathy via impairment of endothelial cell function

Molecular Oral Microbiology, EarlyView.
Abstract Orthotopic allograft transplantation (OAT) is a significant approach to addressing organ failure. However, persistent immune responses to the allograft affect chronic rejection, which induces OAT vasculopathy (OATV) and organ failure. Porphyromonas gingivalis can infiltrate remote organs via the bloodstream, thereby intensifying the severity ...
Chien‐Sung Tsai, Chun‐Yao Huang, Yi‐Ting Tsai, Chun‐Ming Shih, Ze‐Hao Lai, Chen‐Wei Liu, Yi‐Wen Lin, Feng‐Yen Lin   +7 more
wiley   +1 more source