Results 61 to 70 of about 2,567,695 (339)

Communicator, Oct. 2006 [PDF]

open access: yes, 2006
Volume 19, Issue
San Jose State University, Department of Kinesiology
core   +1 more source

A novel technique of contrast-enhanced optical coherence tomography imaging in evaluation of clearance of lipids in human tears [PDF]

open access: yes, 2014
Purpose: The aim of this work was to gather preliminary data in different conditions of healthy eyes, aqueous tear deficient dry eyes, obstructive meibomian gland disease (MGD) and non-obvious obstructive MGD (NOMGD) individuals, using a new, contrast ...
Coronella Franco   +3 more
core   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

Non-invasive investigations of a wall painting using optical coherence tomography and hyperspectral imaging [PDF]

open access: yes, 2011
Multispectral and hyperspectral imaging are efficient methods of measuring spectral reflectance at high spatial resolution. This non-invasive technique has been applied to the imaging of paintings over the last 20 years.
Howard, H   +3 more
core   +1 more source

Microglia limit brain tumor development by restricting tumor cell proliferation and inducing T‐cell immunity

open access: yesMolecular Oncology, EarlyView.
Microglia (BV2) and IL‐4‐treated BMDMs promote astrocytoma clustering and inhibit tumor growth, not shown in other macrophage cells. In vivo, microglial co‐implantation enhances CD8+ T cell infiltration, elevates Granzyme B, lowers circulating MDSCs, and extends survival only in immune‐competent mice, but not in immune‐deficient mice.
Tzu‐Chieh Sun   +5 more
wiley   +1 more source

Beyond backscattering: Optical neuroimaging by BRAD

open access: yes, 2018
Optical coherence tomography (OCT) is a powerful technology for rapid volumetric imaging in biomedicine. The bright field imaging approach of conventional OCT systems is based on the detection of directly backscattered light, thereby waiving the wealth ...
Augustin, Marco   +11 more
core   +1 more source

The influence of ROS1 fusion partners and resistance mechanisms in ROS1‐TKI‐treated non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga   +8 more
wiley   +1 more source

New model of proliferative vitreoretinopathy in rabbit for drug delivery and pharmacodynamic studies

open access: yesDrug Delivery, 2018
Blinding retinal diseases become more epidemic as the population ages. These diseases, such as diabetic retinopathy and macular edema, are of chronic nature and require protracted drug presence at the disease site. A sustained intravitreal porous silicon
Sang Woong Moon   +6 more
doaj   +1 more source

Evaluation of Choroidal Thickness and Volume during the Third Trimester of Pregnancy using Enhanced Depth Imaging Optical Coherence Tomography: A Pilot Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2015
Background: During pregnancy the maternal choroid is exposed to the multiple haemodynamic and hormonal alterations inherent to this physiological condition. These changes may influence choroidal anatomy.
Renata T Rothwell   +4 more
doaj   +1 more source

The multifaceted presentation of syphilitic chorioretinitis examined by multimodal imaging: A case series

open access: yesAmerican Journal of Ophthalmology Case Reports, 2022
Ocular syphilis is also known as the ‘great masquerader’ for the wide variety of clinical features associated with this infection. Although chorioretinitis represents the most frequent manifestation in the posterior pole, other clinical entities can be ...
Lorenzo Ferro Desideri   +7 more
doaj   +1 more source

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