Results 61 to 70 of about 2,884,168 (334)

Regarding the Use of Direct-Acting Anticoagulants of Animal Origin in Diabetic Retinopathy

open access: yesOftalʹmologiâ, 2023
Relevance. Diabetic retinopathy occupies one of the leading places in the frame of blindness and low vision. The very first changes in the retina in diabetic retinopathy are disorders of microcirculation and blood supply in the small vessels of the ...
I. V. Vorobyeva   +5 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

A novel technique of contrast-enhanced optical coherence tomography imaging in evaluation of clearance of lipids in human tears [PDF]

open access: yes, 2014
Purpose: The aim of this work was to gather preliminary data in different conditions of healthy eyes, aqueous tear deficient dry eyes, obstructive meibomian gland disease (MGD) and non-obvious obstructive MGD (NOMGD) individuals, using a new, contrast ...
Coronella Franco   +3 more
core   +1 more source

CLINICAL STUDY REPORT: AN OVERVIEW OF REGULATORY DOCUMENTS AND THE ORGANIZATIONAL AND PRACTICAL ASPECTS OF DEVELOPMENT

open access: yesРазработка и регистрация лекарственных средств, 2019
Clinical study report is one of the main documents during the drug development. The preparation of the clinical study report requires knowledge of Russian and foreign legislation, awareness of guidelines and recommendatioins issued by the professional ...
E. A. Radkova   +3 more
doaj  

Evaluation of optical coherence tomography changes in amblyopia

open access: yesIndian Journal of Ophthalmology
Aim: To study the Central Macular Thickness (CMT) and Retinal nerve fiber layer (RNFL) thickness (RNFLT) using Optical Coherence Tomography (OCT) in cases of amblyopia.
Jawahar L Goyal   +5 more
doaj   +1 more source

Optical coherence tomography and microperimetry in the early diagnosis of glaucoma

open access: yesРоссийский офтальмологический журнал, 2022
The review presents modern possibilities of early diagnosis of glaucoma using optical coherence tomography (OCT), angio-OCT and microperimetry. We analyzed literature data for the last decade, focused on testing patients with suspected glaucoma or ...
U. S. Plyaskina   +2 more
doaj   +1 more source

Mouse Oct-1 contains a composite homeodomain of human Oct-1 and Oct-2 [PDF]

open access: yesNucleic Acids Research, 1993
Members of the Oct family of transcription factors specifically interact with the octamer motif, ATGC-AAAT, a regulatory element important for tissue- and cell-specific transcription as well as for the expression of housekeeping genes. Except for Oct-1, all Oct factors are expressed in a temporally and spatially restricted mode during murine ...
Suzuki, N.   +4 more
openaire   +3 more sources

High-speed OCT light sources and systems [Invited].

open access: yesBiomedical Optics Express, 2017
Imaging speed is one of the most important parameters that define the performance of optical coherence tomography (OCT) systems. During the last two decades, OCT speed has increased by over three orders of magnitude.
T. Klein, R. Huber
semanticscholar   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Global intelligence, co-operation versus accountability: new facets to an old problem [PDF]

open access: yes, 2009
The most important recent change within the realm of intelligence and security services has been the expansion of intelligence co-operation. The growing connectivity between both foreign intelligence services and also domestic security services means ...
Aldrich, Richard J.
core   +1 more source

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