Results 161 to 170 of about 14,957 (210)

DISTRIBUTION AND TURNOVER OF OCTOPAMINE IN TISSUES

Journal of Neurochemistry, 1972
Abstract— Octopamine is a normally occurring amine in several species of animals. Particularly high concentrations are found in the crustacean central nerve cord. In the rat it is specifically localized to sympathetic nerve endings, has a subcellular distribution similar to that of norepinephrine, and is asymmetrically distributed in the CNS.
P B, Molinoff, J, Axelrod
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Octopamine fuels fighting flies

Nature Neuroscience, 2008
The neural basis of aggression is poorly understood. A study in this issue used genetic scalpels to dissect the circuitry of the fly brain and identified a small cluster of octopaminergic neurons that can make a fly fighting mad.
Christopher J, Potter, Liqun, Luo
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Octopamine-Sensitive Adenylate Cyclase: Evidence for a Biological Role of Octopamine in Nervous Tissue

Science, 1973
An adenylate cyclase that is activated specifically by very low concentrations of octopamine has been identified both in homogenates and in intact cells of the thoracic ganglia of an insect nervous system. This enzyme appears to be distinct from two other adenylate cyclases present in the same tissue, which are activated by dopamine and by 5 ...
J A, Nathanson, P, Greengard
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High-affinity octopamine receptors revealed in Drosophila by binding of [3H]octopamine

Neuroscience Letters, 1982
The study describes, for the first time, detection of a putative, high-affinity octopamine receptor by direct binding studies with a radiolabeled ligand. Crude membranes prepared from heads of Drosophila melanogaster bind [3H]octopamine at a level of 0.4 pmol per mg protein with an apparent Kd of 5 nM.
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Octopamine in leeches—I. Distribution of octopamine in Macrobdella decora and Erpobdella octoculata

Comparative Biochemistry and Physiology Part C: Comparative Pharmacology, 1980
Abstract 1. The nervous and other tissues of the leeches M. decora and E. octoculata were asayed for octopamine using a radiochemical-enzymatic technique. 2. Octopamine was found at mean concentrations of 12–40 ng/mg tissue protein in the ganglionated nervous tissue; lesser amounts of 7.4–19 ng/mg tissue protein were observed in the non-ganglionated
Rodney A. Webb, I. Orchard
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-Octopamine as a substrate for monoamine oxidase

Life Sciences, 1979
Abstract m -Octopamine was characterized as substrate for monoamine oxidase (MAO) in rat brain and liver mitochondria. The K m and V max values of the brain enzyme were 735 μM and 32.5 nmoles/mg protein/30 min, and those of the liver enzyme 351 μM and 125 nmoles/mg protein/30 min, respectively.
O, Suzuki, H, Hattori, Y, Katsumata, M, Oya   +3 more
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The Characterization of Presynaptic Octopamine Receptors Modulating Octopamine Release From an Identified Neurone in the Locust

Journal of Experimental Biology, 1998
ABSTRACT Octopamine release has been demonstrated from the dorsal unpaired median neurone to the locust extensor-tibiae muscle (DUMETi) in response to high-[K+] saline. Here, we provide evidence for the existence of presynaptic inhibitory autoreceptors for octopamine on the DUMETi terminals and report on their pharmacological profile ...
, Howell, , Evans
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Octopamine as the transmitter at the firefly lantern: Presence of an octopamine-sensitive and a dopamine-sensitive adenylate cyclase

Comparative Biochemistry and Physiology Part C: Comparative Pharmacology, 1982
Abstract 1. Both octopamine and dopamine cause a large increase in synthesis of cyclic AMP in the lantern of the fireflies Photuris versicolor and Photuris lucicrescens . 2. Lanterns were much more sensitive to octopamine than to dopamine. 3.
J, Copeland, H A, Robertson
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Photoaffinity Labeling of a Neuronal Octopamine Receptor

Journal of Neurochemistry, 1994
Abstract: The invertebrate aminergic neurotransmitter and neuromodulator octopamine (OA) acts at both neuronal and nonneuronal receptors that appear to have distinct pharmacological characteristics. The current work uses a potent and specific OA photoaffinity ligand, tritiated 2(2,6‐diethyl‐4‐azidophenylimino)imidazolidine ([3H]NC‐5Z), to identify and ...
T, Roeder, J A, Nathanson
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ACTION OF OCTOPAMINE AGONISTS AND STEREO ISOMERS AT A SPECIFIC OCTOPAMINE RECEPTOR

Clinical and Experimental Pharmacology and Physiology, 1978
SUMMARY1. (±)‐Octopamine, (±)‐N‐methyl octopamine and (‐)‐α‐methyl octopamine increase the amplitude of contraction of the spontaneously beating ventricle of the mollusc Tapes watlingi through action on a specific octopamine receptor.2. Unlike the excitatory responses to dopamine, noradrenaline or serotonin, the excitatory response of the ventricle to ...
D F, Dougan, D N, Wade
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