Results 141 to 150 of about 1,089,577 (427)

Self-implantable double-layered micro-drug-reservoirs for efficient and controlled ocular drug delivery

Nature Communications, 2018
Eye diseases and injuries impose a significant clinical problem worldwide. Safe and effective ocular drug delivery is, however, challenging due to the presence of ocular barriers.
A. Than, Chenghao Liu, Hao Chang, P. Duong, C. Cheung, Chenjie Xu, Xiaomeng Wang, Peng Chen   +7 more
semanticscholar   +1 more source

Progression of phenotype in Leber's congenital amaurosis with a mutation at the LCA5 locus [PDF]

, 2003
BACKGROUND: Leber’s congenital amaurosis (LCA) accounts for 5% of inherited retinal disease and is usually inherited as an autosomal recessive trait. Genetic and clinical heterogeneity exist.
Inglehearn, C.F., Jafri, H., McKibbin, M.A., Mohamed, M.D., Raashed, Y., Topping, N.C   +5 more
core   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Ocular chemical injuries and their management

Oman Journal of Ophthalmology, 2013
Chemical burns represent potentially blinding ocular injuries and constitute a true ocular emergency requiring immediate assessment and initiation of treatment.
Parul Singh, Manoj Tyagi, Yogesh Kumar, K K Gupta, P D Sharma   +4 more
doaj   +1 more source

Compact CNN Models for On-device Ocular-based User Recognition in Mobile Devices [PDF]

IEEE Symposium on Computational Intelligence in Biometrics and Identity Management (IEEE CIBIM) 2021, 2021
A number of studies have demonstrated the efficacy of deep learning convolutional neural network (CNN) models for ocular-based user recognition in mobile devices. However, these high-performing networks have enormous space and computational complexity due to the millions of parameters and computations involved. These requirements make the deployment of
arxiv  

Toxoplasmosis ocular

Archivos de la Sociedad Española de Oftalmología, 2003
Propósito: Realizar una actualización sobre los aspectos más salientes de la toxoplasmosis ocular. Métodos: En base a publicaciones recientes, reuniones científicas e interpretación de la literatura se intenta clarificar los conceptos sobre distintos aspectos de la toxoplasmosis ocular.
openaire   +3 more sources

Penetration Enhancers in Ocular Drug Delivery

Pharmaceutics, 2019
There are more than 100 recognized disorders of the eye. This makes the development of advanced ocular formulations an important topic in pharmaceutical science.
Roman V Moiseev, Peter W J Morrison, F. Steele, V. Khutoryanskiy   +3 more
semanticscholar   +1 more source

A cohort study on acute ocular motility disorders in pediatric emergency department [PDF]

, 2018
Background: Acute ocular motility disorders (OMDs) in children admitted to Emergency Department (ED) represents a not so rare condition with a wide spectrum of different etiologies.
Ferro, Valentina, Garone, Giacomo, Parisi, Pasquale, Petroni, Sergio, Pirozzi, Nicola, Pro, Stefano, Raucci, Umberto, Reale, Antonino, Rossi, Rossella, Sancetta, Federica, Vanacore, Nicola   +10 more
core   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

A COMPARISON OCULAR [PDF]

JAMA: The Journal of the American Medical Association, 1913
While working on certain changes in the tissues of the guinea-pig, it proved of great advantage, in observing the finer changes, to use two microscopes side by side, one showing the normal tissues and the one the abnormal tissues. On Jan. 29, 1912, I communicated with Mr.
openaire   +3 more sources