Results 21 to 30 of about 239,900 (266)

Abnormal fractional amplitude of low-frequency fluctuations in MOG-lgG optic neuritis patients: a resting-state functional MRI study

Journal of Integrative Neuroscience, 2022
Optic neuritis (ON) is a general term for inflammation of any part of the optic nerve resulting from demyelination or infection. The number of patients with MOG-lgG antibody-related optic neuritis is increasing recently.
Hong-Wu Yang, Qian-Hui Xu, Qiu-Yu Li, Li-Juan Zhang, Hui-Ye Shu, Rong-Bin Liang, Yi-Cong Pan, Yi Shao   +7 more
doaj   +1 more source

Ocular disease and driving [PDF]

Clinical and Experimental Optometry, 2016
As the driving population ages, the number of drivers with visual impairment resulting from ocular disease will increase given the age-related prevalence of ocular disease. The increase in visual impairment in the driving population has a number of implications for driving outcomes. This review summarises current research regarding the impact of common
Wood, Joanne, Black, Alexander
openaire   +3 more sources

Potential factors of cytokeratin fragment 21-1 and cancer embryonic antigen for mediastinal lymph node metastasis in lung cancer

Frontiers in Genetics, 2022
Objective: Lung cancer is a common malignant tumor, characterized by being difficult to detect and lacking specific clinical manifestations. This study aimed to find out the risk factors of mediastinal lymph node metastasis and explore the correlation ...
Jing Tang, Hui-Ye Shu, Tie Sun, Li-Juan Zhang, Min Kang, Ping Ying, Qian Ling, Jie Zou, Xu-Lin Liao, Yi-Xin Wang, Hong Wei, Yi Shao   +11 more
doaj   +1 more source

Enhanced therapeutic effect of PEDF-loaded mesenchymal stem cell-derived small extracellular vesicles against oxygen-induced retinopathy through increased stability and penetrability of PEDF

Journal of Nanobiotechnology, 2023
Background Several common retinal diseases that cause blindness are characterised by pathological neovascularisation accompanied by inflammation and neurodegeneration, including retinopathy of prematurity (ROP), diabetic retinopathy (DR), age-related ...
Ruiyan Fan, Lin Su, Hui Zhang, Yilin Jiang, Zihao Yu, Xiaomin Zhang, Xiaorong Li   +6 more
doaj   +1 more source

Epigenetics in Ocular Diseases [PDF]

Current Genomics, 2013
Epigenetics pertains to heritable alterations in gene expression that do not involve modification of the underlying genomic DNA sequence. Historically, the study of epigenetic mechanisms has focused on DNA methylation and histone modifications, but the concept of epigenetics has been more recently extended to include microRNAs as well.
Liu, Melissa M, Chan, Chi-Chao, Tuo, Jingsheng   +2 more
openaire   +2 more sources

Rapid Response to Trametinib Combined With Chemotherapy for Infant BRAF‐Fused Chiasmatic Glioma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Infants, less than 1 year, with chiasmatic gliomas (ICG) present a major therapeutic challenge due to large tumor size, decreased vision, rapid progression, and poor response to vincristine/carboplatin chemotherapy. The majority have a BRAF fusion, which may respond to downstream MEK inhibitors but response time is slow. There are no safety or
Helen Toledano, Alexander Yelak, Walid Kaadan, Shlomo Caduri, Rivka Friedland, Orli Michaeli, Gad Dotan, Osnat Konen   +7 more
wiley   +1 more source

Metabolomic insights into vitreous humor with therapy outcome in type 2 diabetic retinopathy

BMC Ophthalmology
Background The therapeutic outcome for Type 2 Diabetic Retinopathy (T2DR) following vitrectomy has been unsatisfactory, with no definitive biomarker available to predict treatment response.
Yuxu Hao, Xiangjun She, Gongyu Huang, Xuyang Chu, Shixin Zhao, Zhe Lv, Jiwei Tao, Yun Zhang   +7 more
doaj   +1 more source

Central network changes in patients with advanced monocular blindness: A voxel‐based morphometric study

Brain and Behavior, 2019
Objective To study the changes in gray matter volume (GMV) in patients with advanced monocular blindness (MB) using voxel‐based morphometry (VBM). Methods Thirty‐one patients with advanced MB (25 males and six females) and 31 normal controls (25 males ...
Wen‐Qing Shi, Yin He, Qing‐Hai Li, Li‐Ying Tang, Biao Li, Qi Lin, You‐Lan Min, Qing Yuan, Pei‐Wen Zhu, Rong‐Bing Liang, Yi Shao   +10 more
doaj   +1 more source

Clinical risk factors of carbohydrate antigen-125, cytokeratin fragment 19, and neuron-specific enolase in liver metastases from elderly lung cancer patients

Frontiers in Genetics, 2022
Objective: Lung cancer is a common malignant tumor characterized by challenging detection and lack of specificity in clinical manifestations. To investigate the correlation of tumor markers in the serum with liver metastasis and prognosis of lung cancer ...
Tao Cheng, Jun Chen, Ping Ying, Hong Wei, Huiye Shu, Min Kang, Jie Zou, Qian Ling, Xulin Liao, Yixin Wang, Yi Shao   +10 more
doaj   +1 more source

Cognitive Functioning in Vorinostat‐Treated Pediatric and Young Adult Patients Over the First 180 Days After Hematopoietic Stem Cell Transplant

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Cognitive and psychological difficulties could negatively interfere with treatment adherence and quality of life before and after hematopoietic stem cell transplant (HSCT). Methods to mitigate these changes may have positive effects on treatment success.
Kristen L. Votruba, Michelle Rozwadowski, Thomas Braun, April Rahrig, Edward Peres, Kirsten M. Williams, Vanessa Fabrizio, Julie‐An Talano, Carrie L. Kitko, Nicolas Parnell, Pavan Reddy, Sung Won Choi   +11 more
wiley   +1 more source