Results 41 to 50 of about 2,466,202 (266)

The role of inflammation and fibroblasts in conjunctival scarring in ocular mucous membrane pemphigoid [PDF]

, 2009
Ocular mucous membrane pemphigoid (ocular MMP) is a visually devastating disease where up to 30% of patients become blind due to the consequences of conjunctival inflammation and aggressive fibrosis.
Saw, V.P.J.
core  

Research Progress of Ocular Glymphatic System and Related Ocular Diseases [PDF]

, 2023
Recent discovered ocular glymphatic system, which is facilitated by aquaporin-4 (AQP4) and dependent on the exchange system of aqueous humor-tissue fluid in the perivascular space of retinal arterial and venous, ultimately acts as the role of expelling ...
ZHU Guangyu, CHENG Yuxin, LU Xuejing
core   +2 more sources

Comparison of the repeatability and reproducibility of corneal thickness mapping using optical coherence tomography according to tear film break-up time

BMC Ophthalmology
Background To compare the repeatability and reproducibility of corneal and corneal epithelial thickness mapping using anterior segment optical coherence tomography (AS-OCT) according to tear film break-up time (TBUT).
Kan Lin, Zhiqiang Xu, Hui Wang, Yuzhou Wang, Linzhi Wei, Hongqing Ma, Jian Zhao, Fan Lu, Liang Hu   +8 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Validated prediction model for the development of primary open-angle glaucoma in individuals with ocular hypertension

, 2007
Objective To test the validity and generalizability of the Ocular Hypertension Treatment Study (OHTS) prediction model for the development of primary open-angle glaucoma (POAG) in a large independent sample of untreated ocular hypertensive individuals
N. Orzalesi, Ocular Hypertension Treatment Study Group, European Glaucoma Prevention Study Group, L.M. Rossetti   +3 more
core   +1 more source

An autopsy study of a familial oculopharyngeal muscular dystrophy (OPMD) with distal spread and neurogenic involvement [PDF]

, 1981
An 81-year-old man from a family with a history of oculopharyngeal muscular dystrophy (OPMD) involving 6 members over 4 generations is described. The patient first noted drooping of his eyelids at the age of 65.
Krause, Klaus-Henning, Schmitt, H.-P.
core   +1 more source

Diurnal variations in corneal biomechanics in healthy young adults

BMC Ophthalmology
Purpose To assess the diurnal changes in corneal biomechanics in healthy young adults. Methods At Wenzhou Medical University Eye Hospital in China, a prospective case series.
DaTian Zhu, LuMeng Wang, ZhanXin Qu, Pu Wang, YongYi Yuan, Lan Yang, XinYu Yao, XiaoBo Zheng, HengLi Lian, Chong Wang, JunJie Wang, YuFeng Ye, Ahmed Elsheikh, FangJun Bao, JunHua Li   +14 more
doaj   +1 more source

Metabolomic analysis of aqueous humor reveals potential metabolite biomarkers for differential detection of macular edema

Eye and Vision, 2023
Background Macular edema (ME) is a major complication of retinal disease with multiple mechanisms involved in its development. This study aimed to investigate the metabolite profile of aqueous humor (AH) in patients with ME of different etiologies and ...
Dan Jiang, Congcong Yan, Lina Ge, Chun Yang, Ying Huang, Yau Kei Chan, Chonghua Chen, Wei Chen, Meng Zhou, Bing Lin   +9 more
doaj   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

Differences in choroidal responses to near work between myopic children and young adults

Eye and Vision
Background Near work is generally considered as a risk factor for myopia onset and progression. This study aimed to investigate the choroidal responses to a brief-period of near work in children and young adults.
Mengqi Liu, Yuanyuan Wang, Haoer Li, Yunpeng Zhao, Min Ma, Shihan Xu, Xiaohuan Wei, Ruiyan Xu, Ruikang Tian, Xiangtian Zhou, Hao Wu   +10 more
doaj   +1 more source