Results 71 to 80 of about 2,466,202 (266)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Modification of the technique for detection and follow-up of diseases of the anterior ocular segment using the conjunctival autofluorescence method [PDF]

, 2019
Every person is in constant interaction with the environmental factors, with the sun being the highest energy source. The electromagnetic spectrum includes rays of different wavelengths, with shortwave ultraviolet rays being an invisible, potential ...
Neshkinski, Evgeni; Medical University of Varna, Radeva, Mladena; Medical University of Varna, Grupcheva, Christina; Medical University of Varna, Andreev, Jordan; Medical University of Varna, Boyadzhieva, Mariya; Medical University of Varna   +4 more
core   +7 more sources

Comparison of deep learning-assisted blinking analysis system and Lipiview interferometer in dry eye patients: a cross-sectional study

Eye and Vision
Background Abnormal blinking pattern is associated with ocular surface diseases. However, blink is difficult to analyze due to the rapid movement of eyelids. Deep learning machine (DLM) has been proposed as an optional tool for blinking analysis, but its
Yueping Ren, Han Wen, Furong Bai, Binge Huang, Zhenzhen Wang, Shuwen Zhang, Yaojia Pu, Zhenmin Le, Xianhui Gong, Lei Wang, Wei Chen, Qinxiang Zheng   +11 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Systemic and Bilateral Severe Ocular Toxoplasmosis Resembling Autoimmune Phenomena: A Case Report

Purpose: To present an atypical case of severe bilateral ocular toxoplasmosis with systemic involvement that initially mimicked an autoimmune etiology, posing challenges to its diagnosis and treatment.
Muñoz-Ortiz J., Romero-Santos S., Mejía-Salgado G., de-la-Torre A., Cifuentes-González C., Parra-Tanoux D.   +5 more
core   +1 more source

The role and therapeutic potential of melatonin in age-related ocular diseases [PDF]

, 2017
The eye is continuously exposed to solar UV radiation and pollutants, making it prone to oxidative attacks. In fact, oxidative damage is a major cause of age-related ocular diseases including cataract, glaucoma, age-related macular degeneration and ...
Colligris, Basilio, Almudena Crooke, Jesús Pintor, Crooke Álvarez, Almudena, Huete Toral, Fernando, Basilio Colligris, Fernando Huete-Toral, Pintor Just, Jesús Jerónimo   +7 more
core   +1 more source

Plasma exosomes from patients with active thyroid-associated orbitopathy induce inflammation and fibrosis in orbital fibroblasts

Journal of Translational Medicine
Background The pathogenesis of thyroid-associated orbitopathy (TAO) remains incompletely understand. The interaction between immunocytes and orbital fibroblasts (OFs) play a critical role in orbital inflammatory and fibrosis.
Li Wei, Qinying Huang, Yunhai Tu, Shihan Song, Xiaobo Zhang, Bo Yu, Yufen Liu, Ziwei Li, Qing Huang, Lili Chen, Bo Liu, Shenglan Xu, Tong Li, Xiyuan Liu, Xiaozhou Hu, Weijie Liu, Zai-Long Chi, Wencan Wu   +17 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Clinical Evidence on Allogeneic Blood-Derived Eye Drops in Ocular Surface and Corneal Diseases

PurposeTo systematically review clinical studies on allogeneic blood-derived eye drops in ocular surface and corneal diseases.MethodsA PRISMA-guided search of PubMed, Google Scholar, Scopus, Web of Science, and Embase (1985–September 2025) identified ...
Ghalibafan, Seyyedehfatemeh, Sabater, Alfonso L, John, Ansu Ann, Djalilian, Ali R   +3 more
core   +1 more source

Pathophysiology of ocular surface squamous neoplasia. [PDF]

, 2014
The incidence of ocular surface squamous neoplasia (OSSN) is strongly associated with solar ultraviolet (UV) radiation, HIV and human papilloma virus (HPV). Africa has the highest incidence rates in the world.
Burton, Matthew J., Ohnuma, Shin-ichi, Sagoo, Mandeep S., Burton, Matthew J, Sagoo, Mandeep S, Gichuhi, Stephen   +5 more
core   +1 more source