Results 81 to 90 of about 1,894 (248)

An Alternative Theory of Binocularity

Frontiers in Computational Neuroscience, 2019
The fact that seeing with two eyes is universal among vertebrates raises a problem that has long challenged vision scientists: how do animals with overlapping visual fields combine non-identical right and left eye images to achieve fusion and the ...
Cherlyn J. Ng, Cherlyn J. Ng, Cherlyn J. Ng, Dale Purves, Dale Purves   +4 more
doaj   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Psychophysical Tests Do Not Identify Ocular Dominance Consistently

i-Perception, 2019
Classical sighting or sensory tests are used in clinical practice to identify the dominant eye. Several psychophysical tests were recently proposed to quantify the magnitude of dominance but whether their results agree was never investigated.
Miguel A. García-Pérez, Eli Peli
doaj   +1 more source

Pull-push neuromodulation of cortical plasticity enables rapid bi-directional shifts in ocular dominance

eLife, 2020
Neuromodulatory systems are essential for remodeling glutamatergic connectivity during experience-dependent cortical plasticity. This permissive/enabling function of neuromodulators has been associated with their capacity to facilitate the induction of ...
Su Z Hong, Shiyong Huang, Daniel Severin, Alfredo Kirkwood   +3 more
doaj   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Ocular Dominance Stability and Reading Skill: A Controversial Relationship

, 2011
Purpose. Evidence is mixed concerning the relationship between stability of ocular dominance and reading deficits. Contrasting results may be due to the use of different tests of dominance, different samples of readers, and different scoring methods. The
ZOCCOLOTTI, Pierluigi, Maria De Luca, Pierluigi Zoccolotti, Donatella Spinelli, Fabrizio Zeri, SPINELLI, Donatella   +5 more
core   +1 more source

Monocular delay during visually guided actions is as effective as monocular deprivation in driving ocular dominance plasticity

Scientific Reports
In normally sighted adult volunteers, applying a monocular patch for a few hours produces a short-term shift of ocular dominance in favor of the deprived eye—a phenomenon often interpreted as a form of homeostatic plasticity.
Cecilia Steinwurzel, Giacomo Pennella, Maria Concetta Morrone, Giulio Sandini, Paola Binda   +4 more
doaj   +1 more source

Layer specific regulation of critical period timing and maturation of mouse visual cortex by endocannabinoids

iScience
Summary: Plasticity during the critical period is important for the functional maturation of cortical neurons. While characteristics of plasticity are diverse among cortical layers, it is unknown whether critical period timing is controlled by a common ...
Taisuke Yoneda, Katsuro Kameyama, Takahiro Gotou, Keiko Terata, Masahiro Takagi, Yumiko Yoshimura, Kenji Sakimura, Masanobu Kano, Yoshio Hata   +8 more
doaj   +1 more source