Results 221 to 230 of about 4,507 (256)

Reactivation of Ocular Dominance Plasticity in the Adult Visual Cortex

open access: yesScience, 2002
In young animals, monocular deprivation leads to an ocular dominance shift, whereas in adults after the critical period there is no such shift. Chondroitin sulphate proteoglycans (CSPGs) are components of the extracellular matrix (ECM) inhibitory for axonal sprouting.
Tommaso Pizzorusso   +2 more
exaly   +5 more sources

Lifelong learning: ocular dominance plasticity in mouse visual cortex

open access: yesCurrent Opinion in Neurobiology, 2006
Ocular dominance plasticity has long served as a successful model for examining how cortical circuits are shaped by experience. In this paradigm, altered retinal activity caused by unilateral eye-lid closure leads to dramatic shifts in the binocular response properties of neurons in the visual cortex.
Hofer, Sonja B.   +3 more
openaire   +5 more sources

Dissociating ocular dominance column development and ocular dominance plasticity: a neurotrophic model

open access: yesBiological Cybernetics, 2002
Recent experimental data indicate that both neurotrophic factors (NTFs) and intracortical inhibitory circuitry are implicated in the development and plasticity of ocular dominance columns. We extend a neurotrophic model of developmental synaptic plasticity, which previously failed to account correctly for the differences between monocular deprivation ...
Terry Elliott, Nigel R. Shadbolt
openaire   +4 more sources

the regulation of critical period for ocular dominance plasticity [PDF]

open access: yes, 2014
The experience dependent plasticity of stimulus selectivity, including ocular dominance plasticity, is highest during a postnatal critical period. The developmental constraint on this plasticity is thought to underlie the inability to recover from amblyopia in adults, which has generated interest in understanding the mechanisms for the initiation and ...
Gu, Yu
openaire   +3 more sources

Ocular dominance plasticity: Molecular mechanisms revisited

Journal of Comparative Neurology, 2020
Abstract Ocular dominance plasticity (ODP) is a type of cortical plasticity operating in visual cortex of mammals that are endowed with binocular vision based on the competition‐driven disparity. Earlier, a molecular mechanism was proposed that catecholamines play an important role in the maintenance of ODP in kittens. Having survived
Takuji Kasamatsu, Kazuyuki Imamura
openaire   +2 more sources

Molecular basis for induction of ocular dominance plasticity

Journal of Neurobiology, 1999
The most dramatic example of experience-dependent cortical plasticity is the shift in ocular dominance that occurs in visual cortex as a consequence of monocular deprivation during early postnatal life. Many of the basic properties of this type of synaptic plasticity have been described in detail.
M F, Bear, C D, Rittenhouse
openaire   +2 more sources

Stimulus for Rapid Ocular Dominance Plasticity in Visual Cortex

Journal of Neurophysiology, 2006
Although it has been known for decades that monocular deprivation shifts ocular dominance in kitten striate cortex, uncertainty persists about the adequate stimulus for deprivation-induced losses of cortical responsiveness. In the current study we compared the effects of 2 days of lid closure and 2 days of monocular blur using an overcorrecting ...
Cynthia D, Rittenhouse   +6 more
openaire   +2 more sources

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