Results 201 to 210 of about 32,854 (248)
Advanced Materials Technologies, EarlyView.Desktop vacuum thermoforming enables rapid, low‐cost fabrication of 96‐channel polystyrene culture chips with very thin imaging interfaces. The resulting platform supports cell lines, primary cells, and patient‐derived organoids, and enables high‐resolution confocal microscopy and single‐cell visualization, providing an accessible approach for advanced
Aleksandra Fomina +5 more
wiley +1 more source
Characterized Ecoflex Polydimethylsiloxane (PDMS) Hybrids for Advanced Flexible Devices
Advanced Materials Technologies, EarlyView.Ecoflex–PDMS hybrids are systematically characterized to identify an optimal composition that balances stretchability, optical transparency, and plasma bonding, enabling multifunctional applications in stretchable microfluidics, flexible sensing, and soft robotics.
Xiaoyue Kang +10 more
wiley +1 more source
Advanced Materials Technologies, EarlyView.Transparent microelectrode arrays enable simultaneous optical and electrical electrophysiology with high spatiotemporal resolution, allowing multimodal observations of dynamic biological systems. Advances in materials and device architectures improve device performance by addressing key trade‐offs between optical transparency, impedance, and ...
Michael Abraham Listyawan +6 more
wiley +1 more source
Advanced Materials Technologies, EarlyView.A liquid metal‐based strain‐sensing architecture to measure the deformation of a circular diaphragm against obstructed surfaces is formulated using finite element modeling and confocal imaging to establish the mechanical framework and is utilized to control diaphragm‐induced confinement on a bead array, as validated by biomolecular loading level ...
Abdullah‐Bin Siddique +4 more
wiley +1 more source
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Expert Opinion on Drug Delivery, 2006
Drug delivery to the eye is hampered by anatomical factors, including the corneal epithelium, the blood-aqueous barrier and the blood-retinal barrier. This review aims to outline the major routes of ocular drug delivery, including systemic, topical, periocular and intravitreal. The pharmacokinetics, the disadvantages and the clinical relevance of these
Deepta Ghate, Henry F Edelhauser
exaly +4 more sources
Drug delivery to the eye is hampered by anatomical factors, including the corneal epithelium, the blood-aqueous barrier and the blood-retinal barrier. This review aims to outline the major routes of ocular drug delivery, including systemic, topical, periocular and intravitreal. The pharmacokinetics, the disadvantages and the clinical relevance of these
Deepta Ghate, Henry F Edelhauser
exaly +4 more sources
Penetration Enhancers in Ocular Drug Delivery [PDF]
Pharmaceutics, 2019 There are more than 100 recognized disorders of the eye. This makes the development of advanced ocular formulations an important topic in pharmaceutical science. One of the ways to improve drug delivery to the eye is the use of penetration enhancers. These are defined as compounds capable of enhancing drug permeability across ocular membranes.
Peter W J Morrison +2 more
exaly +5 more sources
Nanomaterials for Ocular Drug Delivery
Macromolecular Bioscience, 2012AbstractEfficient drug delivery to the eye remains a challenging task for pharmaceutical scientists. Due to the various anatomical barriers and the clearance mechanisms prevailing in the eye, conventional drug delivery systems, such as eye drop solutions, suffer from low bioavailability.
Shengyan, Liu +2 more
openaire +2 more sources
Review of Ocular Drug Delivery
Current Drug Delivery, 2006Successful treatment of eye diseases requires effective concentration of drug at the eye for sufficient period of time. Conventional ocular drug delivery including eye drops, systemic administration, ophthalmic ointments, is no longer sufficient to combat ocular diseases.
Yasmin, Sultana +3 more
openaire +2 more sources
2016
Although the eye is an accessible organ for direct drug application, ocular drug delivery remains a major challenge due to multiple barriers within the eye. Key barriers include static barriers imposed by the cornea, conjunctiva, and retinal pigment epithelium and dynamic barriers including tear turnover and blood and lymphatic clearance mechanisms ...
Burcin, Yavuz, Uday B, Kompella
openaire +2 more sources
Although the eye is an accessible organ for direct drug application, ocular drug delivery remains a major challenge due to multiple barriers within the eye. Key barriers include static barriers imposed by the cornea, conjunctiva, and retinal pigment epithelium and dynamic barriers including tear turnover and blood and lymphatic clearance mechanisms ...
Burcin, Yavuz, Uday B, Kompella
openaire +2 more sources
Advances in Ocular Drug Delivery
Current Eye Research, 2012Eye drops have long been the primary ocular drug delivery dosage form used to treat ocular disorders ranging from superficial conditions to intravitreal diseases. The ocular anatomical structure and physiological protective mechanisms are one of the most formidable barriers to drug penetration that have significantly reduced the drug's efficacy and ...
Rawas-Qalaji, Mutasem +1 more
openaire +3 more sources