Results 91 to 100 of about 102,886 (302)

The role of central corneal thickness in the diagnosis of glaucoma

Indian Journal of Ophthalmology, 2000
Purpose: To determine the effect of central corneal thickness (CCT) on applanation tonometry and any resultant misclassification of normals as ocular hypertension.
Thomas Ravi, Korah Sanita, Muliyil Jayaprakash   +2 more
doaj  

Legumain Restrains Granuloma Formation by Inhibiting mTORC1/STAT1‐Mediated M1 Macrophage Polarization in Sarcoidosis

Advanced Science, EarlyView.
Legumain (LGMN) is upregulated in macrophages during sarcoid‑like granuloma formation. Macrophage‑derived LGMN binds to integrin αvβ3 and suppresses mTORC1/STAT1 signaling to restrain M1 macrophage polarization. Intratracheal delivery of lipid nanoparticles carrying Lgmn plasmid DNA (pDNA) elevates LGMN expression and effectively attenuates pulmonary ...
Mengyuan Liu, Yueyin Han, Bingbing Xie, Lili Zhu, Wenxiu Xu, Yinzhen Han, Yue Liao, Shuwei Gao, Dingyuan Jiang, Jing Geng, Zhen Li, Yinan Hu, Huaping Dai   +12 more
wiley   +1 more source

Corneal Biomechanics for Ocular Hypertension, Primary Open-Angle Glaucoma, and Amyloidotic Glaucoma: A Comparative Study by Corvis ST

Clinical Ophthalmology, 2022
Nisa Silva,1 André Ferreira,1,2 Pedro Manuel Baptista,1 Ana Figueiredo,1 Rita Reis,1 Isabel Sampaio,1 João Beirão,1,3 Riccardo Vinciguerra,4,5 Pedro Menéres,1,3 Maria João Menéres1,3 1Ophthalmology Department, Centro Hospitalar Universitário do Porto ...
Silva N, Ferreira A, Baptista PM, Figueiredo A, Reis R, Sampaio I, Beirão J, Vinciguerra R, Menéres P, Menéres MJ   +9 more
doaj  

Endogenous hypercortisolism inducing reversible ocular hypertension

American Journal of Ophthalmology Case Reports, 2019
Purpose: To describe the clinical findings of two patients with reversible ocular hypertension secondary to endogenous hypercortisolism. Design: Retrospective, observational case series.
Shane Griffin, Timothy Boyce, Beth Edmunds, William Hills, Marjorie Grafe, Shandiz Tehrani   +5 more
doaj   +1 more source

Matrix Metalloproteinases and Glaucoma Treatment. [PDF]

, 2020
Matrix metalloproteinases (MMPs) are a family of proteolytic enzymes that degrade extracellular matrix (ECM) components such as collagen and have important roles in multiple biological processes, including development and tissue remodeling, both in ...
Dibas, Mohammed, Robinson, Michael R, Stamer, W Daniel, Weinreb, Robert N   +3 more
core  

Biomechanical, ultrastructural, and electrophysiological characterization of the non-human primate experimental glaucoma model. [PDF]

, 2017
Laser-induced experimental glaucoma (ExGl) in non-human primates (NHPs) is a common animal model for ocular drug development. While many features of human hypertensive glaucoma are replicated in this model, structural and functional changes in the ...
Christian, Brian J, Eaton, J Seth, Gong, Haiyan, Miller, Paul E, Morgan, Joshua T, Murphy, Christopher J, Nork, T Michael, Raghunathan, VijayKrishna, Rasmussen, Carol A, Russell, Paul, Ver Hoeve, James N, Yang, Chen-Yuan Charlie   +11 more
core   +2 more sources

Semiconducting Polymer Nanoparticles Enable Light‐Controlled Bidirectional Modulation of Nitric Oxide in Endothelial Cells

Advanced Science, EarlyView.
Bimodal modulation of nitric oxide in endothelial cells is achieved by light‐sensitive polymer nanoparticles. In dark, P3HT/PEDOT:PSS NPs boost intracellular ·NO, upregulate both endothelial and induced nitric oxide synthase, and drive a metabolic shift toward glycolysis.
Camilla Marzuoli, Andrea Pianetti, Elena Mancinelli, Anthea Villano, Matteo Vailati, Paola Lagonegro, Miryam Criado‐Gonzalez, Montserrat Climent, Hansel Comas‐Rojas, Leonardo Elia, Francesco Moccia, Gabriele Tullii, Maria Rosa Antognazza   +12 more
wiley   +1 more source

Incidence of new coding for dry eye and ocular infection in open-angle glaucoma and ocular hypertension patients treated with prostaglandin analogs: Retrospective analysis of three medical/pharmacy claims databases

BMC Ophthalmology, 2011
Background To investigate the clinical relevance of two different preservative formulations, we compared 1-year incidence rates of additional coding of dry eye, ocular infection, or ocular surface disease (either dry eye or ocular infection) in open ...
Kotak Sameer, Schwartz Gail F, Mardekian Jack, Fain Joel M   +3 more
doaj   +1 more source

Heroin withdrawal as a possible cause of acute concomitant esotropia in adults [PDF]

, 2001
Aim: To report the possible effects of heroin withdrawal on binocular vision. Methods: To present a case series of patients in whom esotropia developed on cessation of heroin use.
Firth, A.Y.
core  

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

Advanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu, Haolin Fan, Minwoo Kim, Tong Zhou, Pinyi Yang, Lingdi Zhao, Yiran Wang, Ziyuan Che, Chia‐Wei Liu, Bingbing Li, Yangzhi Zhu   +10 more
wiley   +1 more source