Results 31 to 40 of about 11,610 (293)

Retinal and optic nerve degeneration in α-mannosidosis

Orphanet Journal of Rare Diseases, 2018
Background α-mannosidosis is a rare, autosomal-recessive, lysosomal storage disease caused by a deficient activity of α-mannosidase. Typical symptoms include intellectual, motor and hearing impairment, facial coarsening, and musculoskeletal abnormalities.
Juliane Matlach, Thea Zindel, Yasmina Amraoui, Laila Arash-Kaps, Julia B. Hennermann, Susanne Pitz   +5 more
doaj   +1 more source

OCULAR MOTILITY DISORDERS WITH SPECIAL EMPHASIS ON MULTIPLE SCLEROSIS [PDF]

, 2019
International audienceMultiple sclerosis (MS) is a demyelinating disease of the central nervous system leading to disability, especially in young patients.
Tilikete, Caroline
core   +2 more sources

A protocol to quantify cross-sectional and longitudinal differences in duction patterns

Frontiers in Neuroscience
Currently, there is no established system for quantifying patterns of ocular ductions. This poses challenges in tracking the onset and evolution of ocular motility disorders, as current clinical methodologies rely on subjective observations of individual
Kevin T. Willeford, Victoria Copel, Hua Rong   +2 more
doaj   +1 more source

Eye Segmentation Method for Telehealth: Application to the Myasthenia Gravis Physical Examination

Sensors, 2023
Due to the precautions put in place during the COVID-19 pandemic, utilization of telemedicine has increased quickly for patient care and clinical trials.
Quentin Lesport, Guillaume Joerger, Henry J. Kaminski, Helen Girma, Sienna McNett, Mohammad Abu-Rub, Marc Garbey   +6 more
doaj   +1 more source

Guidelines for Pediatric Radiotherapy Simulation: A Report From the Children's Oncology Group Radiation Oncology Discipline

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei, Stephen Mihalcik, Sujith Baliga, Young Kwok, Dana Casey, Eric Ehler, Christiane Burton, John C. Breneman, Daphne A. Haas‐Kogan, Suzanne L. Wolden, Arnold C. Paulino, Nadia N. Laack, Natia Esiashvili, Sarah Milgrom, Christine Hill‐Kayser, Thomas J. Fitzgerald, John A. Kalapurakal, Chia‐Ho Hua   +17 more
wiley   +1 more source

Diplopia After Coronary Revascularization

Acta Médica Portuguesa, 2020
Percutaneous coronary intervention is a coronary revascularization procedure that may rarely result in thromboembolic events. Although infrequent, ophthalmological complications of percutaneous interventions include a wide range of clinical presentations,
Joana Braga, Filipe Neves, João Costa, Dália Meira   +3 more
doaj   +1 more source

Visual function, ocular motility and ocular characteristics in patients with mitochondrial complex I deficiency [PDF]

, 2012
. Purpose: The aims of the present study were to investigate visual function, ocular motility and ocular characteristics in children and young adults with complex I deficiency. Material and Methods: In a prospective study with longitudinal follow-up, the
Fahnehjelm, Kristina Teär,, von Döbeln, Ulrika,, Naess, Karin,, Wiberg, Maria,, Olsson, Monica,, Martin, Lene,, Ygge, Jan,   +6 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Pearls and pitfalls in the management of Duane syndrome

Taiwan Journal of Ophthalmology, 2017
Duane syndrome (DS) is a common form of congenital cranial dysinnervation disorders. The ocular motility pattern lies in a wide clinical spectrum, and the choice of treatment must be individualized depending on the severity of the clinical findings ...
Seyhan B Ozkan
doaj   +1 more source