Results 41 to 50 of about 11,554 (291)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Analyzing clinical and electrophysiological characteristics of Paroxysmal Dyskinesia

Journal of Research in Medical Sciences, 2011
The classification, clinical and electrophysiological characteristics, treatment outcome and pathogenesis of paroxysmal dyskinesia were summarized and analyzed. Paroxysmal dyskinesia was classified into three types.
Jue-qian Zhou, Lie-min Zhou, Zi-yan Fang, Qian Wang, Zi-yi Chen, Li-bai Yang, Su-da Chen, Xiao-dong Cai   +7 more
doaj  

Severe Ophthalmological Complications of Thyroid Disease are Rare in Ibadan, Southwestern Nigeria: Results of a Pilot Study

Ophthalmology and Eye Diseases, 2016
Background Ocular manifestations of thyroid dysfunction constitute a wide clinical spectrum ranging from minor ocular discomfort, lid retraction, lid lag and ocular injection, to sight threatening eyeball protusion and optic nerve compression.
Olufunmilola A. Ogun, Jokotade O. Adeleye   +1 more
doaj   +1 more source

Eye signs in stroke

Annals of Indian Academy of Neurology, 2022
A large part of the central nervous system is involved in the normal functioning of the vision, and hence vision can be affected in a stroke patient.
Rajeshwar Sahonta, Ivy Sebastian, Sanjit Aaron, Appaswamy T Prabakhar, Anupriya Arthur, Jeyaraj D Pandian   +5 more
doaj   +1 more source

Additional file 5: of Development of a core outcome set for amblyopia, strabismus and ocular motility disorders: a review to identify outcome measures

, 2019
Table S3.3. Ocular motility disorders included studies. Included studies for ocular motility disorders arranged by sub-condition, study ID, title, outcome measure domain, outcome measurement and time of measurement.
Samia Jabri (6318161), Jamie Kirkham (179425), Fiona Rowe (3136911)   +2 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Abducens Nerve Schwannoma: Case Report and Literature Review

Brazilian Neurosurgery, 2022
The authors describe a rare case of abducens nerve schwannoma, manifested with headache and diplopia, associated to right side cerebellar syndrome. During surgery, the authors identified that the origin of the tumor was from the abducens nerve, and the ...
Guilherme Finger, Bruno Loyola Godoy, Bruna Koeche da Silva, Rafael de Mello, Janio Nogueira, Antonio Aversa do Souto   +5 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Ocular Neuromyotonia Resolved with Oxcarbazepine

, 2023
Ocular neuromyotonia is a disorder characterized by tonic contraction of one or more extraocular muscles. The pathophysiology is incompletely understood but thought to be due to damaged myelin sheath in ocular motor nerves, triggering crosstalk between ...
Danielle Isen; Michael Vaphiades; Lanning Kline
core