Results 61 to 70 of about 11,610 (293)
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
Ocular Motor Instability: A Neurodiagnostic Sign of Prenuclear Disease [PDF]
, 2023 Accurate diagnosis of efferent visual system disease in Neuro-ophthalmology involves the classification of clinical signs as prenuclear, nuclear, or infranuclear in origin.
Michael C. Brodsky
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
ROCK inhibitors in ocular disease
ADMET and DMPK, 2016 Rho kinases (ROCKs) have a crucial role in actin-cytoskeletal reorganization and thus are involved in broad aspects of cell motility, from smooth muscle contraction to neurite outgrowth.
Eva Halasz, Ellen Townes-Anderson
doaj +1 more source
[Ocular motility disorders in a patient with Fabry's disease] [PDF]
, 2009 Fabry's disease (FD) is a rare lysosomal storage disorder. Early cerebral manifestations are a major and often life-threatening burden of the disease. We present a 38-year-old male FD patient with a prior history of six different episodes of stroke and ...
Fiore, B;Klopfer, M;Schwebig, C;Wiescher, A;Lanzl, I
core +1 more source
Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source
Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati +10 more
wiley +1 more source
Ocular Motility in Childhood Migraine [PDF]
, 1992 Headache in childhood has a remarkably constant occurrence in different socio-economic, cultural, geographic and ethnic groups. Bille\u27s study on the incidence and prevalence of headache in children is most often quoted.
Charles G. Maitland, MD
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown +6 more
wiley +1 more source
Ocular Neuromyotonia: A More Common Entity than Previously Thought [PDF]
, 2023 Ocular neuromyotonia is an uncommon condition classically associated with post-radiation changes. It is defined as slowing of a saccade to primary position in one eye only after sustained lateral gaze.
Michael Rosenberg
core