Study of differential cytokine IFN-γ,IL-10，TGF-β and IL-17 level in patients with myasthenia gravis with antibodies against AChR ,MuSK and LRP4 [PDF]
, 2016 目的:通过采用酶联免疫吸附(ELISA)法检测重症肌无力(myastheniagravis，MG)患者血清乙酰胆碱受体抗体(AChR-Ab)，肌肉特异性酪氨酸激酶抗体(MuSK-Ab)，低密度脂蛋白受体相关蛋白4抗体（LRP4-Ab）浓度，探讨AChR-Ab，MuSK-Ab，LRP4-Ab与重症肌无力临床分型、及与细胞因子干扰素-γ(IFN-γ)，白细胞介素-10（IL-10），生长转化因子-β（TGF-β），白细胞介素-17（IL-17）的关系。 方法： 1.本研究分为重症肌无力组和健康对照组 ...
李若冰
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Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review
British Journal of Pharmacology, Volume 183, Issue 9, Page 1779-1813, May 2026.Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos +16 more
wiley +1 more source
Frontalis sling procedure for ocular myasthenia gravis
Clinical Ophthalmology, 2012 Shinichi Asamura1, Hirohiko Kakizaki2, Mitsuhiro Enjyo1, Takahiro Hashimoto1, Noritaka Isogai11Department of Plastic and Reconstructive Surgery, Kinki University School of Medicine, Osakasayama, Osaka, Japan; 2Department of Ophthalmology, Aichi Medical ...
Isogai N +4 more
doaj
Disfagia e Disartria. Forma Invulgar de Apresentação da Miastenia Gravis [PDF]
, 2007 Myasthenia Gravis is an autoimmune disorder that generally presents with ocular symptoms, specially diplopia and ptosis. Dysphagia may be a manifestation of the generalised type of the disease, but rarely is its presenting feature. The authors describe a
Alcântara, J +5 more
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European Journal of Neurology, Volume 33, Issue 5, May 2026.In the Vivacity‐MG3 study, clinical response to nipocalimab was assessed using the MG‐ADL and QMG measures. Nipocalimab treatment improves gMG symptoms earlier than placebo and provides sustained disease control over the 24‐week double‐blind period.
Tuan Vu +12 more
wiley +1 more source
Оцінка тривожності у хворих на міастенію [PDF]
, 2018 У статті представлено результати дослідження тривожності у хворих на міастенію залежно від імунологічного типу, тривалості та клінічної форми захворювання. Мета роботи — дослідити рівень тривожності у дорослих, хворих на міастенію. Матеріал і методи.
Кальбус, О.І.
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Anàlisi del títol d'anticossos anti-achr i la seva correlació clínica en pacients amb miastenia gravis seropositiva [PDF]
, 2013 Els anticossos contra el receptor de l'acetilcolina representen el principal mecanisme patogènic en la Miastènia Gravis, però la seva utilitat com a biomarcador durant el seguiment de la malaltia és ...
Illa Sendra, I. +3 more
core +1 more source
Acute Bilateral Ophthalmoplegias [PDF]
, 1977 Bilateral ophthalmoplegia is that condition of weakness or paralysis involving one or more ocular muscles in each eye. Its sudden appearance due to an acute ocular myopathy is indeed unusual. Swash reported a single patient with acute necrotizing orbital
Selhorst, John B.
core +1 more source
بررسی وضعيت سرولوژيک و الکتروفيزيولوژيک بيماران مبتلا به مياستنی گراويس [PDF]
, 2013 زمينه و هدف: مياستنی گراويس نوعی اختلال خود ايمنی است که به طور اساسي در اثر آنتی بادیهای ضد رسپتور استيل کولين در محل اتصال عصب به عضله ايجاد شده و کاهش رسپتورهای مذکور سبب اختلال در انتقال نوروترانسميتر و خستگی و ضعف عضلانی میشود.
اميرزرگر, علی اکبر +6 more
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Effect of pregnancy and birth on the course of myasthenia gravis before or after transsternal radical thymectomy [PDF]
, 2017 Objective: Myasthenia gravis (MG) affects women at childbearing age. Therefore, the question arises if these patients should become pregnant and if thymectomy has a positive effect on the course of MG in pregnant patients.
Carboni, Gianluca +4 more
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