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Advanced Science, EarlyView.This study presents a human Bone (and Bone Marrow)‐on‐a‐Chip model based on native human bone scaffolds and autologous cells. Dynamic perfusion and sequential cell seeding replicate the physiological bone remodeling process in vitro, enabling the long‐term culture of functional, mature bone marrow immune subpopulations.
Nina Stelzer +17 more
wiley +1 more source
Artificial intelligence-assisted diagnosis of ocular surface diseases [PDF]
Frontiers in Cell and Developmental Biology, 2023 Qi Dai
exaly +2 more sources
Ocular Surface, 2017 Coexistence of an ocular surface disease can mask the typical features of ocular surface squamous neoplasia (OSSN). The purpose of this study was to evaluate high resolution optical coherence tomography (HR-OCT) as an adjunct in the detection and ...
Jianhua Wang, Anat Galor, Carol L Karp
exaly +2 more sources
Current Evidence on the Ocular Surface Microbiota and Related Diseases
Microorganisms, 2020 The ocular surface microbiota refers to the resident non-pathogenic microorganisms that colonize conjunctiva and cornea. Several studies have shown that ocular surface epithelial cells can respond selectively to specific components of ocular pathogenic ...
Carla Zannella +2 more
exaly +3 more sources
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Gut Microbiome and Its Influence On Ocular Surface and Ocular Surface Diseases
Eye & Contact Lens: Science & Clinical Practice, 2022Abstract: The gut microbiome plays a substantial immunologic and pathophysiologic role in maintaining the health of the host, and dysregulation of this dynamic ecosystem has been associated with several inflammatory conditions. Many studies have explored the influence of gut microbiota on the ocular surface and whether gut microbiota impact ...
Shambhawi Thakur, John D. Sheppard
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Immunobiologicals and ocular surface disease
Current Opinion in Allergy & Clinical Immunology, 2022Purpose of review Immunobiologicals have surfaced to become a new cornerstone of treatment for a wide spectrum of inflammatory disorders with an immune basis. The targets have ranged from autoimmune conditions to transplantation, and now more into atopic inflammatory disorders with primary targets of asthma and atopic ...
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A Review of Topical and Systemic Vitamin Supplementation in Ocular Surface Diseases [PDF]
Nutrients, 2021 Paolo Fogagnolo +2 more
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The ocular surface in thyroid diseases
Current Opinion in Allergy & Clinical Immunology, 2010The purpose of the present review is to describe recent insights into the pathomechanism of ocular surface impairment in the course of thyroid dysfunctions. The review focuses in particular on Graves' ophthalmopathy as the majority of the literature is published on this topic.Mechanical factors were thought, until now, to be the indirect causes of ...
VERSURA, PIERA, CAMPOS, EMILIO
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Contact Lenses for Ocular Surface Disease
Eye & Contact Lens: Science & Clinical Practice, 2022Abstract: Ocular surface disease can be difficult to manage, causing patients discomfort and vision loss. Therapeutic contact lenses are an important treatment option that is often neglected because it is conventional wisdom that eyes that are dry or irritated are not good candidates for contact lens.
Xueyang Wang, Deborah S. Jacobs
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