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Zeb1 Promotes Odontoblast Differentiation in a Stage-Dependent Manner

Journal of dentistry research, 2021
A comprehensive study of odontoblastic differentiation is essential to understand the process of tooth development and to achieve the ability of tooth regeneration in the future.
Y. Xiao   +7 more
semanticscholar   +1 more source

Fam20C overexpression in odontoblasts regulates dentin formation and odontoblast differentiation

Journal of Molecular Histology, 2023
FAM20C phosphorylates secretory proteins at S-x-E/pS motifs, and previous studies of Fam20C-dificient mice revealed that FAM20C played essential roles in bone and tooth formation. Inactivation of FAM20C in mice led to hypophosphatemia that masks direct effect of FAM20C in these tissues, and consequently the direct role of FAM20C remains unknown.
Kohei Naniwa   +7 more
openaire   +2 more sources

S100A4 is expressed in human odontoblasts and odontoblast-like cells

Tissue and Cell, 2022
The calcium-binding protein S100A4 has been found in fibroblasts in many tissues. It has been well studied in the regulating process of inflammation and tumor metastasis. However, as a calcium regulating protein, its expression in the dental pulp has not yet been elucidated.
Xue, Cai, Lu, Zhang, Xiaoyan, Wang
openaire   +2 more sources

SALL1 regulates commitment of odontoblast lineages by interacting with RUNX2 to remodel open chromatin regions

Stem Cells, 2020
Mouse dental papilla cells (mDPCs) derive from cranial neural crest cells and maintain mesenchymal stem cell characteristics. The differentiation of neural crest cells into odontoblasts is orchestrated by transcription factors regulating the expression ...
Lin YuXiu   +7 more
semanticscholar   +1 more source

Midkine Promotes Odontoblast-like Differentiation and Tertiary Dentin Formation

Journal of dentistry research, 2020
Autophagy is an intracellular self-degradation process that is essential for tissue development, cell differentiation, and survival. Nevertheless, the role of autophagy in tooth development has not been definitively identified. The goal of this study was
Y.H. Park   +6 more
semanticscholar   +1 more source

Odontoblasts in odontogenic tumors

Medical Hypotheses, 2013
Odontoblasts are secretory cells displaying epithelial and mesenchymal features, which exist in a monolayer at the interface between the dentin and pulp of a tooth. During embryogenesis, these cells form a dentin shell and throughout life continue to produce dentin while, also acting as sensor cells helping to mediate tooth sensitivity. In this process,
Nadine C, Milos   +2 more
openaire   +2 more sources

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