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The Genes Involved in Dentinogenesis [PDF]

Organogenesis, 2022
The development and repair of dentin are strictly regulated by hundreds of genes. Abnormal dentin development is directly caused by gene mutations and dysregulation. Understanding and mastering this signal network is of great significance to the study of tooth development, tissue regeneration, aging, and repair and the treatment of dental diseases.
Shiyi Chen, Han Xie, Shouliang Zhao
exaly   +3 more sources

6-Methylsulfinylhexyl isothiocyanate activates carbonic anhydrase-dependent HCO₃ ^-/H⁺/Na⁺/Ca²⁺ transport via SLC4As-NHE-NCX-PMCA axis in odontoblasts. [PDF]

J Physiol
Abstract figure legend 6‐Methylsulfinylhexyl isothiocyanate (6‐MSITC, hexaraphane), a wasabi sulfinyl compound, activates intracellular carbonic anhydrase (CA)‐mediated sequential HCO3−, Na+, H+ and Ca2+ transport through an activation axis involving HCO3−‐transporting solute carrier family 4 (SLC4As), the Na+–H+ exchanger (NHE), the Na+–Ca2+ exchanger
Furusawa Y, Kimura M, Okunishi I, Ouchi T, Kurashima R, Katou-Yamada T, Kuroda H, Sugita M, Furusawa M, Shibukawa Y.   +9 more
europepmc   +2 more sources

Gene expression profiles identify key factors in inflammatory odontoblastic dental pulp stem cell differentiation via TNFα/C5L2 [PDF]

Frontiers in Genetics
IntroductionInflammation is a complex host response to harmful infections or injuries, playing beneficial and detrimental roles in tissue regeneration.
Muhammad Irfan, Ji Hyun Kim, Sreelekshmi Sreekumar, Seung Chung   +3 more
doaj   +2 more sources

Prosthodontic rehabilitation of dentinogenesis imperfecta

Contemporary Clinical Dentistry, 2011
Dentinogenesis imperfecta and its prosthodontic management is a challenging task. Treatment protocol varies according to clinical case. Although various reports in the literature suggest general guidelines for treatment planning, the present case report ...
Anil Goud, Saee Deshpande
doaj   +3 more sources

Accidental Diagnosis of Type VII Osteogenesis Imperfecta in an Infant Presenting With Pneumonia and Rickets‐Like Rib Fractures: A Case Report [PDF]

Clin Case Rep
ABSTRACT This case report describes a newborn diagnosed with Type VII Osteogenesis Imperfecta (OI) following an incidental finding of rib fractures during evaluation for pneumonia. The patient presented with multiple fractures, including deformities and callus formations in the ribs and extremities, initially raising concerns for differential diagnoses
Parviz S, Hooshyar D.
europepmc   +2 more sources

Dentinogenesis imperfecta: A case report

Journal of Indian Society of Pedodontics and Preventive Dentistry, 2008
Dentinogenesis imperfecta is an autosomal dominant disorder of tooth development characterized by the presence of opalescent dentin, resulting in a dusky blue to brownish discoloration of the teeth.
Subramaniam P, Mathew S, Sugnani S
doaj   +3 more sources

Hyaluronic acid as a biomaterial for dental pulp regeneration: a systematic review of preclinical studies [PDF]

Frontiers in Bioengineering and Biotechnology
IntroductionWith the current advancements in regenerative medicine, it has become necessary to refine the current regenerative endodontic procedure (REP).
Azal Hadi Al-Masoody, Azal Hadi Al-Masoody, Mahshid Hodjat, Tahereh Sadat Jafarzadeh Kashi   +3 more
doaj   +2 more sources

Establishment of Dental Pulp Cell Culture System for Analyzing Dentinogenesis in Mouse Incisors [PDF]

Dentistry Journal
Background: The dentin–pulp complex plays a vital role in tooth health. Dentin forms the main body the tooth and continues to form throughout life to maintain homeostasis and provide protection against deleterious external stimuli.
Yuka Kato, Insoon Chang, Satoshi Yokose
doaj   +2 more sources

Esthetic-based Dental Management of Dentinogenesis Imperfecta in a 2.5-year-old Child [PDF]

Journal of Kerman University of Medical Sciences, 2021
Background: Dentinogenesis imperfecta (DI) is an autosomal dominant (AD) hereditary dentin disorder, which occurs in the absence of any systemic disorder. The patients with DI presented rapid and severe attrition in primary teeth, which causes functional
Leyli Sadri, Soroush Sadri, Najmeh Akhlaghi, hamid sarlak   +3 more
doaj   +3 more sources

METTL3 enhances dentinogenesis differentiation of dental pulp stem cells via increasing GDF6 and STC1 mRNA stability

BMC Oral Health, 2023
Background The dentinogenesis differentiation of dental pulp stem cells (DPSCs) is controlled by the spatio-temporal expression of differentiation related genes.
Yue Pan, Ying Liu, Dixin Cui, Sihan Yu, Yachuan Zhou, Xin Zhou, Wei Du, Liwei Zheng, Mian Wan   +8 more
doaj   +1 more source