Results 41 to 50 of about 3,951 (175)

Regenerative Endodontic Treatment in Dentinogenesis Imperfecta-Induced Apical Periodontitis

Case Reports in Dentistry
Pulp involvement of immature permanent teeth with dentinogenesis imperfecta is challenging and could lead to extraction. A case of dentinogenesis imperfecta-induced periapical periodontitis of an immature permanent tooth was treated with regenerative ...
Ying Liao, Ting Pan, Xianghui Xing
doaj   +1 more source

Dentine Regeneration With Calcium Strontium Silicate: In Vitro Odontogenic Differentiation, Antimicrobial Activity, Immunomodulation and In Vivo Pulpotomy in Rat Molars

International Endodontic Journal, EarlyView.
ABSTRACT Aim This study examined the in vitro and in vivo performance of calcium strontium silicate (CSR) as a novel biomaterial for vital pulp therapy (VPT), assessing its odontogenic differentiation, antibacterial activity, immunomodulation, inflammatory response and dentine regeneration potential compared to calcium silicate (CS) and Mineral ...
Mohamed Mahmoud Abdalla, Vidhyashree Rajasekar, Heba Ahmed, Mengyu Huang, Cynthia Kar Yung Yiu   +4 more
wiley   +1 more source

BDNF/TrkB Is a Crucial Regulator in the Inflammation-Mediated Odontoblastic Differentiation of Dental Pulp Stem Cells

Cells, 2023
The odontoblastic differentiation of dental pulp stem cells (DPSCs) associated with caries injury happens in an inflammatory context. We recently demonstrated that there is a link between inflammation and dental tissue regeneration, identified via ...
Ji-Hyun Kim, Muhammad Irfan, Md Akil Hossain, Anne George, Seung Chung   +4 more
doaj   +1 more source

Inflammation‐Regeneration Axis of Dental Pulp Stem Cells: Wnt/NF‐κB Crosstalk

International Endodontic Journal, EarlyView.
ABSTRACT Background Inflammation critically determines dental pulp regenerative outcomes, with dental pulp stem cells (DPSCs) orchestrating tissue homeostasis through differentiation, self‐renewal and immunomodulation processes dynamically regulated by Wnt/β‐catenin and NF‐κB signaling crosstalk.
V. Rajasekar, M. Huang, M. M. Abdalla, P. Neelakantan, C. K. Y. Yiu   +4 more
wiley   +1 more source

An Updated Classification of Hydraulic Cements Used in Dentistry

International Endodontic Journal, EarlyView.
ABSTRACT Mineral trioxide aggregate (MTA) was the first hydraulic cement used in endodontics. It is composed of Portland cement, a binder in concrete, and bismuth oxide to enhance the radiopacity. MTA was introduced in dentistry to be used as a root‐end filling material and also to repair root perforations.
Josette Camilleri
wiley   +1 more source

The Role of Neuropeptide Y in Dental Pulp: Balancing Neurogenic Inflammation and Pain Modulation

International Endodontic Journal, EarlyView.
ABSTRACT Background Dental pulp is a densely innervated, low‐compliance tissue in which neurogenic inflammation can rapidly escalate into oedema, raised intrapulpal pressure, microvascular compromise, and pain. While Substance P (SP) and Calcitonin gene‐related peptide (CGRP) are well‐established drivers of pulp vasodilation, the Neuroopeptide Y (NPY ...
Javier Caviedes‐Bucheli, Esteban Ulate, Hugo‐Roberto Munoz, Nestor Ríos‐Osorio   +3 more
wiley   +1 more source

Tubule and microbranch variations in human dentine: A quantitative 3D study with serial block‐face scanning electron microscopy

Journal of Microscopy, EarlyView.
ABSTRACT Objective: Microbranches exist within dentine, providing a network of fluid filled connections between tubules. This study used serial block‐face scanning electron microscopy to generate 3D volumes of dentine from different tooth locations, allowing for investigations of the microbranch morphology, the microbranch network characteristics and ...
Bethany Harding, Patricia Goggin, James Thompson, Behrad Mahmoodi, Katy Rankin, Philipp Schneider, Richard Cook   +6 more
wiley   +1 more source

Promoting dentinogenesis of DPSCs through inhibiting microRNA-218 by using magnetic nanocarrier delivery

Journal of the Formosan Medical Association, 2019
Purpose: The purposes of this study are to explore the roles of microRNA-218 (miR-218) delivered by a newly designed magnetic nanocarrier: GCC-Fe3O4 (GCC-Fe) in dentinogenesis potentials of human dental pulp stem cells (DPSCs).
Karen Chang, Rung-Shu Chen, Fu-Hsiung Chang, Min-Huey Chen   +3 more
doaj   +1 more source

Oral Manifestations of Non Vascular Ehlers‐Danlos Syndrome Cross‐Sectional Study

Oral Diseases, EarlyView.
ABSTRACT Background Ehlers–Danlos syndromes are rare hereditary connective tissue disorders; however, their oral manifestations remain poorly characterized in molecularly confirmed individuals. The aim of this study was to describe the oral phenotype of patients with non‐vascular Ehlers‐Danlos syndromes compared to healthy controls.
Aude Grand, Benjamin P. J. Fournier, Grégoire Chevalier, Karelle Benistan, François Côme Ferré   +4 more
wiley   +1 more source

Constitutive expression of spliced X-box binding protein 1 inhibits dentin formation in mice

Frontiers in Physiology
Upon endoplasmic reticulum (ER) stress, inositol-requiring enzyme 1 (IRE1) is activated, which subsequently converts an unspliced X-box binding protein 1 (XBP1U) mRNA to a spliced mRNA that encodes a potent XBP1S transcription factor.
Qian Xu, Jiahe Li, Hua Zhang, Suzhen Wang, Chunlin Qin, Yongbo Lu   +5 more
doaj   +1 more source