Results 21 to 30 of about 5,434 (210)

Circadian rhythm disruption impairs time-dependent dentine regeneration and reprograms the late-stage dental proteome in a mouse pulp injury model [PDF]

Frontiers in Pharmacology
Circadian rhythms coordinate metabolic and regenerative programs, yet their contribution to pulp healing and tertiary dentinogenesis remains unclear. Here, we investigated whether chronic circadian rhythm disruption (CRD) alters time-dependent dentine ...
Melike Guvendi, Melike Guvendi, Hayriye E. Yelkenci, Elif Ozbay, Halil I. Koc, Olgu E. Tok, Olgu E. Tok, Serdar Altunay, Serdar Altunay, Ertugrul Kilic, Ertugrul Kilic, Mustafa Gundogar, Mustafa Gundogar, Mustafa C. Beker, Mustafa C. Beker   +14 more
doaj   +2 more sources

Chromatin Remodeller BRD9 Orchestrates Odontoblastic Differentiation via Coordinating RUNX2-KLF4. [PDF]

Cell Prolif
During odontoblast lineage commitment, the chromatin remodeller BRD9 acts as a critical epigenetic coordinator, orchestrating the chromatin landscape to facilitate synergistic binding of key transcription factors RUNX2 and KLF4 to target loci for odontogenesis.
Zeng W, Lin Y, Gao Y, Huang D, Li Y, Ruan H, Yuan G, Liu H, Chen Z.   +8 more
europepmc   +2 more sources

Multidisciplinary Oral Rehabilitation in Osteogenesis Imperfecta: 18-Year-Old Case Report. [PDF]

Clin Case Rep
ABSTRACT Osteogenesis imperfecta (OI) is a hereditary connective tissue disorder characterized by bone fragility and Type I collagen defects. Although dentinogenesis imperfecta (DI) is a classic manifestation, patients with OI may experience significant dental deterioration even in its absence due to inherent dentinal weakness.
Mozafari PM, Noghani MT, Kashani I, Beyragh R.   +3 more
europepmc   +2 more sources

Single-Cell Virtual Perturbation Screening Identifies STAT3 as a Key Regulator of Dentinogenesis. [PDF]

Cell Prolif
STAT3 promotes odontoblast differentiation in dental mesenchymal cells by transcriptionally regulating WNT2B via the canonical Wnt/β‐catenin signalling pathway. These findings elucidate a mechanism underlying dentine development. ABSTRACT Dentine formation constitutes a physiological process precisely regulated by signal transduction modules governing ...
Zhu Y, Xu H, Zhang Z, Sun S, Huang Z, Gao X, Pan H, Huang X, Liu Y, Wang X, Jia H, Dai Q, Jiang L.   +12 more
europepmc   +2 more sources

METTL3 enhances dentinogenesis differentiation of dental pulp stem cells via increasing GDF6 and STC1 mRNA stability

BMC Oral Health, 2023
Background The dentinogenesis differentiation of dental pulp stem cells (DPSCs) is controlled by the spatio-temporal expression of differentiation related genes.
Yue Pan, Ying Liu, Dixin Cui, Sihan Yu, Yachuan Zhou, Xin Zhou, Wei Du, Liwei Zheng, Mian Wan   +8 more
doaj   +1 more source

Dentinogenesis imperfecta: The Genetic Causes and Outcomes [PDF]

, 2021
Dentinogenesis imperfecta (DI) is a genetic disorder characterized by dentin discoloration, tooth development irregularities, and decreased tooth strength. This autosomal dominant disorder is identified in individuals of all ages.
Johnson, Sydney P, Ms.
core   +1 more source

Tratamiento integral y control a 12 años de paciente con Dentinogénesis Imperfecta tipo I

Revista de Odontopediatria Latinoamericana, 2021
La Dentinogénesis Imperfecta es una anomalía dentaria determinada genéticamente y caracterizada clínicamente por una apariencia ámbar opalescente de la dentina.
Ingrid Clarisa Guitelman, Diana Elizabeth Fridman, Marcela Adriana Moya   +2 more
doaj   +1 more source

Influence of Hydrogen Peroxide on Mineralization in Dental Pulp Cells: A Systematic Review

Frontiers in Dental Medicine, 2021
Background: Dental bleaching agents show the ability to permeate through dental hard tissues, which may lead to pulp tissue changes. This systematic review (PROSPERO register: CRD42020213767) is aimed at understanding the effects of bleaching agents on ...
Alexandre Henrique dos Reis-Prado, Isadora Rodrigues Grossi, Hebertt Gonzaga dos Santos Chaves, Carolina Bosso André, Luís Fernando dos Santos Alves Morgan, André Luiz Fraga Briso, Luciano Tavares Angelo Cintra, Francine Benetti   +7 more
doaj   +1 more source

Dental Management of a Child with Dentinogenesis Imperfecta: A Case Report

Frontiers in Dentistry, 2016
Dentinogenesis imperfecta (DI) is a hereditary dentin defect caused by an autosomal dominant mutation in dentin sialophosphoprotein gene. Defective dentin development results in discolored teeth that are prone to wear and fracture.
Najmeh Akhlaghi, Ali-Reza Eshghi, Mehrnaz Mohamadpour   +2 more
doaj   +1 more source

EFFECT OF MATERNAL VITAMIN D3 DEFICIENCY ON DENTINOGENESIS IN RATS (EXPERIMENTAL STUDY) [PDF]

Alexandria Dental Journal, 2022
Introduction: Vitamin D3 insufficiency has become a severe health problem that affects more than one billion people worldwide. Maternal vitamin D3 deficiency can induce dentin defects during tooth development.
Khadiga Kawana, Hossam eldin moustafa, Amira elnozahy, Ahmed Saleh   +3 more
doaj   +1 more source