6-Methylsulfinylhexyl isothiocyanate activates carbonic anhydrase-dependent HCO<sub>3</sub> <sup>-</sup>/H<sup>+</sup>/Na<sup>+</sup>/Ca<sup>2+</sup> transport via SLC4As-NHE-NCX-PMCA axis in odontoblasts. [PDF]
Abstract figure legend 6‐Methylsulfinylhexyl isothiocyanate (6‐MSITC, hexaraphane), a wasabi sulfinyl compound, activates intracellular carbonic anhydrase (CA)‐mediated sequential HCO3−, Na+, H+ and Ca2+ transport through an activation axis involving HCO3−‐transporting solute carrier family 4 (SLC4As), the Na+–H+ exchanger (NHE), the Na+–Ca2+ exchanger
Furusawa Y +9 more
europepmc +2 more sources
Experimental light-microscopic study of pathological dentinogenesis [PDF]
The aim of this paper was to analyze pathological dentinogenesis in initial and subsequent developmental stages in relation to the type and intensity of irritations, by means of light microscopy.
Stevanović Radoje, Vojinović Jovan
doaj +1 more source
Influence of Hydrogen Peroxide on Mineralization in Dental Pulp Cells: A Systematic Review
Background: Dental bleaching agents show the ability to permeate through dental hard tissues, which may lead to pulp tissue changes. This systematic review (PROSPERO register: CRD42020213767) is aimed at understanding the effects of bleaching agents on ...
Alexandre Henrique dos Reis-Prado +7 more
doaj +1 more source
Immunomodulation stimulates the innervation of engineered tooth organ [PDF]
The sensory innervation of the dental mesenchyme is essential for tooth function and protection. Sensory innervation of the dental pulp is mediated by axons originating from the trigeminal ganglia and is strictly regulated in time. Teeth can develop from
Bécavin, Thibault +5 more
core +9 more sources
Chromatin remodeling, specifically the tissue-specific regulation in mineralized tissues, is an understudied avenue of gene regulation. Here we show that Baf45a and Baf45d, two Baf45 homologs belong to ATPase-dependent SWI/SNF chromatin remodeling ...
Theodore Busby +6 more
doaj +1 more source
Wnt/β-catenin signaling is known to play essential roles in odontoblast differentiation and reparative dentin formation. Various Wnt activators including LiCl have been increasingly studied for their effectiveness to induce repair of the dentin-pulp ...
Anushree Vijaykumar, Mina Mina
doaj +1 more source
Minimally invasive orthodontics: elastodontic therapy in a growing patient affected by Dentinogenesis Imperfecta [PDF]
AIM: The aim of the study was to report the use of an elastodontic therapy in a growing patient affected by Dentinogenesis Imperfecta, second class malocclusion, deep bite and lower arch crowding from the deciduous dentition to permanent one. CASE
IERARDO, GAETANO +4 more
core +1 more source
The relevance applying in the adhesive protocol in devital teeth
Aim. To determine the relevance of the application of the chlorhexidine adhesive Protocol in devital teeth.Materials and methods. A systematic review of the literature in the electronic databases Google Scholar and Pubmed was conducted.
Z. S. Khabadze +5 more
doaj +1 more source
Genotype-phenotype correlation study in 364 osteogenesis imperfecta Italian patients [PDF]
Osteogenesis imperfecta (OI) is a rare genetic disorder of the connective tissue and 90% of cases are due to dominant mutations in COL1A1 and COL1A2 genes.
Boarini, Manila +11 more
core +1 more source
Conditional Knockout of Raptor/mTORC1 Results in Dentin Malformation
mTORC1 signaling plays an important role in extracellular and intracellular signals, including growth factors, nutrients, energy metabolism, and stress. However, the functional role of mTORC1 in dentinogenesis is unknown.
Furong Xie +11 more
doaj +1 more source

