Results 31 to 40 of about 5,434 (210)

Baf45a Mediated Chromatin Remodeling Promotes Transcriptional Activation for Osteogenesis and Odontogenesis

open access: yesFrontiers in Endocrinology, 2022
Chromatin remodeling, specifically the tissue-specific regulation in mineralized tissues, is an understudied avenue of gene regulation. Here we show that Baf45a and Baf45d, two Baf45 homologs belong to ATPase-dependent SWI/SNF chromatin remodeling ...
Theodore Busby   +6 more
doaj   +1 more source

Lithium Chloride Exerts Differential Effects on Dentinogenesis and Osteogenesis in Primary Pulp Cultures

open access: yesFrontiers in Dental Medicine, 2021
Wnt/β-catenin signaling is known to play essential roles in odontoblast differentiation and reparative dentin formation. Various Wnt activators including LiCl have been increasingly studied for their effectiveness to induce repair of the dentin-pulp ...
Anushree Vijaykumar, Mina Mina
doaj   +1 more source

Conditional Knockout of Raptor/mTORC1 Results in Dentin Malformation

open access: yesFrontiers in Physiology, 2019
mTORC1 signaling plays an important role in extracellular and intracellular signals, including growth factors, nutrients, energy metabolism, and stress. However, the functional role of mTORC1 in dentinogenesis is unknown.
Furong Xie   +11 more
doaj   +1 more source

Towards a New Concept of Regenerative Endodontics Based on Mesenchymal Stem Cell-Derived Secretomes Products

open access: yesBioengineering, 2022
The teeth, made up of hard and soft tissues, represent complex functioning structures of the oral cavity, which are frequently affected by processes that cause structural damage that can lead to their loss.
Luis A. Costa   +3 more
doaj   +1 more source

Bioactive molecules for regenerative pulp capping [PDF]

open access: yesEuropean Cells & Materials, 2021
Since the discovery of bioactive molecules sequestered in dentine, researchers have been exploring ways to harness their activities for dental regeneration. One specific area, discussed in this review, is that of dental-pulp capping. Dental-pulp caps are
LLE Whitehouse   +3 more
doaj   +1 more source

Laporan Kasus: Dentinogenesis Imperfekta [PDF]

open access: yes, 2019
Dentinogenesis imperfecta is the one of most common hereditary disorder of dentin formation, especially at histodifferentiation stage. It reported have to an incidences of 1 in 8000.
Abdurokhman, Evellyn Islami   +1 more
core   +1 more source

The effects of 4-Phenylbutyric acid on ER stress during mouse tooth development

open access: yesFrontiers in Physiology, 2023
Introduction: During tooth development, proper protein folding and trafficking are significant processes as newly synthesized proteins proceed to form designated tissues.
Eui-Seon Lee   +12 more
doaj   +1 more source

High pH-Sensitive Store-Operated Ca2+ Entry Mediated by Ca2+ Release-Activated Ca2+ Channels in Rat Odontoblasts

open access: yesFrontiers in Physiology, 2018
Odontoblasts play a crucial role in dentin formation and sensory transduction following the application of stimuli to the dentin surface. Various exogenous and endogenous stimuli elicit an increase in the intracellular free calcium concentration ([Ca2+]i)
Maki Kimura   +7 more
doaj   +1 more source

The relevance applying in the adhesive protocol in devital teeth

open access: yesЭндодонтия Today, 2021
Aim. To determine the relevance of the application of the chlorhexidine adhesive Protocol in devital teeth.Materials and methods. A systematic review of the literature in the electronic databases Google Scholar and Pubmed was conducted.
Z. S. Khabadze   +5 more
doaj   +1 more source

Protein S100-A7 Derived from Digested Dentin Is a Critical Molecule for Dentin Pulp Regeneration

open access: yesCells, 2019
Dentin consists of inorganic hard tissue and organic dentin matrix components (DMCs). Various kinds of bioactive molecules are included in DMCs and some of them can be released after digestion by endogenous matrix metalloproteinases (MMPs) in the caries ...
Shungo Komichi   +8 more
doaj   +1 more source

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