Results 51 to 60 of about 3,951 (175)

Long‐term stability of conventional non‐regenerative periodontal treatment for furcation defects

Periodontology 2000, EarlyView.
Abstract Background Furcation involvement (FI) in multi‐rooted teeth poses significant challenges in periodontal therapy due to complex anatomy and difficulty in achieving effective maintenance. FI is associated with increased periodontal destruction, especially in sites with narrow furcation entrances and deep root concavities.
Guo‐Hao Lin, April Martinez, Vincent Li, Eric Lee, Kang‐Wei Tu, Richard Kao, Hom‐Lay Wang   +6 more
wiley   +1 more source

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

Gingival and Periodontal Diseases and Conditions in Children and Adolescents: Consensus Report

Journal of Clinical Periodontology, Volume 53, Issue 7, Page 1068-1099, July 2026.
ABSTRACT Background The objectives of this Focused Workshop were to update the epidemiology, aetiology, risk factors, diagnosis and management of gingival and periodontal diseases and conditions in children and adolescents, and to explore the applicability of the 2018 Classification in children and adolescents.
Iain Chapple, Sotiria Gizani, Mariano Sanz, Dominique Declerck, Phoebus Madianos, Valerie Clerehugh, Monique Danser, Esti Davidovich, Janet Davies, Nikos Donos, Elisabeth Dursun, Elena Figuero, Filippo Graziani, Mervi Gursoy, Soren Jepsen, Clara Joseph, Moritz Kebschull, Norbert Kraemer, Tina Lambrinaki, Rodrigo López, David J. Manton, Joerg Meyle, Ana Molina, Lior Shapira, Cheryl Somani, Georgios Tsilingaridis, Svante Twetman, Nicola West, Biniyam Wondimu, Ferranti Wong, David Herrera   +30 more
wiley   +1 more source

Evaluation of the performance of ChatGPT‐4 and ChatGPT‐4o as a learning tool in endodontics

International Endodontic Journal, Volume 59, Issue 6, Page 1057-1069, June 2026.
Abstract Aims The aim of this study was to evaluate the accuracy and consistency of responses given by two different versions of Chat Generative Pre‐trained Transformer (ChatGPT), ChatGPT‐4, and ChatGPT‐4o, to multiple‐choice questions prepared from undergraduate endodontic education topics at different times of the day and on different days ...
Esra Arılı Öztürk, Ceren Turan Gökduman, Burhan Can Çanakçi   +2 more
wiley   +1 more source

C5L2 CRISPR KO enhances dental pulp stem cell-mediated dentinogenesis via TrkB under TNFα-induced inflammation

Frontiers in Cell and Developmental Biology
Background and Objectives: Dental caries is one of the most common human pathological conditions resulting from the invasion of bacteria into the dentin. Current treatment options are limited.
Muhammad Irfan, Hassan Marzban, Seung Chung   +2 more
doaj   +1 more source

Histone Acetylation as a Regenerative Target in the Dentine-Pulp Complex

Frontiers in Genetics, 2020
If dental caries (or tooth decay) progresses without intervention, the infection will advance through the dentine leading to severe pulpal inflammation (irreversible pulpitis) and pulp death.
Yukako Yamauchi, Paul Roy Cooper, Emi Shimizu, Yoshifumi Kobayashi, Anthony J. Smith, Henry Fergus Duncan   +5 more
doaj   +1 more source

Noggin inhibition of mouse dentinogenesis

Journal of Oral Biosciences, 2020
The Bone Morphogenetic Proteins (BMPs) direct tooth development and still express in the adult tooth. We hypothesized that inhibition of BMP function would therefore disrupt dentinogenesis by differentiated odontoblasts.We generated mice overexpressing the BMP-inhibitory protein Noggin in differentiated odontoblasts and osteocytes under control of a ...
Priyam, Jani, Hua, Zhang, M Douglas, Benson, Chunlin, Qin   +3 more
openaire   +3 more sources

Preserving Pulp Vitality With Full Pulpotomy Using Mineral Trioxide Aggregate in Permanent Molars Affected With Symptomatic Irreversible Pulpitis: A 12–24 Months Case Series

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Maintaining and preserving the remaining pulp vitality is the latest minimally invasive and conservative treatment option. In‐depth knowledge of pulp inflammation and its reparative process has enhanced the adaptation of full pulpotomy as a vital pulp therapy.
Neelam D. Chandwani, Anjali Gayke, Ranjana Deshmukh, Mohmed Isaqali Karobari   +3 more
wiley   +1 more source

Hemicentin-1 is an essential extracellular matrix component during tooth root formation by promoting mesenchymal cells differentiation

Frontiers in Cell and Developmental Biology
Introduction: Root dentin formation is an important process in tooth development. We tried to identify potential genes that regulate root dentin formation which could be potentially used for the regeneration and repair of defective or damaged dental ...
Yujia Cui, Chuwen Li, Chuwen Li, Hanyang Wang, Lei Li, Jing Xie, Xuedong Zhou, Hai Zhang, Jianxun Sun   +8 more
doaj   +1 more source

Reduced Dietary Protein Induces Changes in the Dental Proteome

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, Volume 346, Issue 2, Page 107-127, March 2026.
Low dietary protein (10%) from normal (20%) does change protein expression in tooth proteome and alter developmental pathways. Among the significant protein expressions changes are actin‐based myosins, tooth, and bone development proteins. Perplexingly tooth size is not altered, suggesting more nuanced phenotypic response to low dietary protein in ...
Robert W. Burroughs, Christopher J. Percival, Natasha S. Vitek   +2 more
wiley   +1 more source