Results 91 to 100 of about 9,236 (227)

New technologies in oral reconstructive medicine: Consensus report of the AAP/OF/SEPA Workshop

Journal of Periodontology, Volume 97, Issue S1, Page S8-S32, September 2026.
Abstract Background The objectives of this Workshop were to evaluate the efficacy of scaffolding technologies for horizontal and vertical ridge augmentation; to evaluate the efficacy of substitute scaffolds for soft tissue augmentation in the context of implant therapy; to evaluate the efficacy of cells and/or biologics combined with scaffolds for ...
Mariano Sanz, Sašo Ivanovski, José Nart, Frank Schwarz, Hom‐Lay Wang, Tara L. Aghaloo, Bilal Al‐Nawas, Gustavo Avila‐Ortiz, Shayan Barootchi, Juan Blanco, Gonzalo Blasi, Nikolaos Donos, Balazs Feher, Irina F. Dragan, Maria L. Geisinger, Adrián Guerrero, Effie Ioannidou, Darnell Kaigler, Yvonne Hernandez‐Kapila, Purnima S. Kumar, Liran Levin, Antonio Liñares, George A. Mandelaris, Paula Matesanz‐Pérez, Alberto Monje, Eduardo Montero, Alberto Ortiz‐Vigón, Joan Otomo‐Corgel, Flavia Q. Pirih, Ausra Ramanauskaite, Isabella Rocchietta, Vanessa Ruiz‐Magaz, Hanae Saito, Nerea Sánchez, Javier Sanz Esporrin, Anton Sculean, Florian M. Thieringer, Daniel S. Thoma, Cristina Valles, Diego Velásquez, David T. Wu, William V. Giannobile   +41 more
wiley   +1 more source

Teneurin-2 presence in rat and human odontoblasts. [PDF]

, 2017
Teneurins are transmembrane proteins consisting of four paralogues (Ten-1-4), notably expressed in the central nervous system during development. All teneurins contain a bioactive peptide in their carboxyl terminal named teneurin C-terminal associated ...
A. Gonçalves, E Ervolino, Lovejoy, D. A., K. R. Torres-da-Silva, I. Z. Guiati, Torres-da-Silvali, K. R., I. M. Beneti, G W L Tessarin, C. A. Casatti, Ervolino, E., C A Dias, Guiati, I. Z. [UNESP], Beneti, I. M. [UNESP], Beneti, I. M., K R Torres-da-Silva, A Gonçalves, I M Beneti, Casatti, C. A. [UNESP], I Z Guiati, D A Lovejoy, Ervolino, E. [UNESP], Torres-da-Silvali, K. R. [UNESP], Tessarin, G. W. L. [UNESP], G. W. L. Tessarin, Goncalves, A., Guiati, I. Z., Casatti, C. A., Goncalves, A. [UNESP], Dias, C. A., C. A. Dias, Tessarin, G. W. L., C A Casatti, Dias, C. A. [UNESP], E. Ervolino, D. A. Lovejoy   +34 more
core   +1 more source

Membrana preformativa: Unveiling the unexplored facets of dental development

Journal of Oral Biology and Craniofacial Research
Aim: Odontogenesis is a complex and highly regulated biological process that involves a range of molecular mechanisms. Among these, Ki67 and Cyclin D1 are crucial cell cycle regulators that play pivotal roles in controlling cell proliferation during ...
Sakshi Sikaria, Suganya Panneer Selvam, Ramya Ramadoss, Sandhya Sundar   +3 more
doaj   +1 more source

In Vivo Base Editing Partially Rescues Bone Dysplasia in a Mouse Model of Hutchinson‐Gilford Progeria Syndrome

Aging Cell, Volume 25, Issue 9, September 2026.
Hutchinson‐Gilford progeria syndrome (HGPS) is a premature aging disorder caused by a mutation in LMNA that produces the toxic progerin protein. In this study, an adenine base editor delivered via AAV9 achieved partial gene correction in HGPS mice when given at two weeks of age, partially rescuing bone structural and gene expression parameters and ...
Wayne A. Cabral, Caleb M. Grenko, Diana Yeritsyan, Indeevar Beeram, Shubham Laiwala, Lukas R. Johnson, Urraca L. Tavarez, Tingfen Yan, Stephen M. Wincovitch, Luke W. Koblan, Xin D. Gao, Meirui An, Narisu Narisu, Leslie G. Biesecker, David R. Liu, Ara Nazarian, Francis S. Collins, Michael R. Erdos   +17 more
wiley   +1 more source

The roles of odontoblasts in dental pulp innate immunity

, 2018
Summary: Odontoblasts located in the outermost layer of dental pulp form a natural barrier between mineralized tissues, dentin, and soft tissues, dental pulp, of the vital tooth, and they first recognize caries-related pathogens and sense external ...
Kouji Hirao, Tadashi Nakanishi, Hitomi Kuramoto, Daisuke Takegawa, Hiromichi Yumoto, Yuki Hosokawa, Takashi Matsuo   +6 more
core   +1 more source

Na+/Ca2+ exchanger isoforms of rat odontoblasts and osteoblasts

, 2000
In odontoblasts as well as osteoblasts, a number of mechanisms for the inflow and extrusion of Ca2+ have been demonstrated. The entrance of Ca2+ ions into odontoblasts occurs mainly through voltage-gated calcium channels. Extrusion of Ca2+ is found to be
Gritli Linde, Amel,, Lundquist, Patrik,, Linde, Anders,, Lundgren, Ted,   +3 more
core   +1 more source

Effects of Interferon-γ on odontoblastic differentiation and mineralization of odontoblast-like cells

Inflammation and Regeneration, 2015
Introduction: Dentinogenesis is regulated by cytokines and growth factors, and modulated by alterations in the extracellular microenvironment. Dental matrix protein-1 (DMP-1), which is predominantly expressed in odontoblasts, is required during the early and late stages of odontogenesis.
Nakagawa, Aika, Okinaga, Toshinori, Ariyoshi, Wataru, Morotomi, Takahiko, Kitamura, Chiaki, Nishihara, Tatsuji   +5 more
openaire   +2 more sources

Dentine Regeneration With Calcium Strontium Silicate: In Vitro Odontogenic Differentiation, Antimicrobial Activity, Immunomodulation and In Vivo Pulpotomy in Rat Molars

International Endodontic Journal, Volume 59, Issue 9, Page 1871-1886, September 2026.
ABSTRACT Aim This study examined the in vitro and in vivo performance of calcium strontium silicate (CSR) as a novel biomaterial for vital pulp therapy (VPT), assessing its odontogenic differentiation, antibacterial activity, immunomodulation, inflammatory response and dentine regeneration potential compared to calcium silicate (CS) and Mineral ...
Mohamed Mahmoud Abdalla, Vidhyashree Rajasekar, Heba Ahmed, Mengyu Huang, Cynthia Kar Yung Yiu   +4 more
wiley   +1 more source

Ca2+ Channels in Odontoblasts

Journal of Oral Biosciences, 2010
Abstract Odontoblasts, well-polarized columnar cells at the periphery of the dental pulp, originate from neural crest cells. They are primarily involved in dentin formation (dentinogenesis) as sites of the synthesis and secretion of collagenous and non-collagenous matrix proteins, and also participate in the directional transport of Ca 2+ from the ...
Shibukawa, Yoshiyuki, Tsumura, Maki, Sato, Masaki, Ichikawa, Hideki, Momose, Yasunori, Tazaki, Masakazu   +5 more
openaire   +1 more source

Distribution of the amelogenin protein in developing, injured and carious human teeth

Frontiers in Physiology, 2014
Amelogenin is the major enamel matrix protein with key roles in amelogenesis. Although for many decades amelogenin was considered to be exclusively expressed by ameloblasts, more recent studies have shown that amelogenin is also expressed in other dental
Thimios eMitsiadis, Anna eFilatova, Gianpaolo ePapaccio, Michel eGoldberg, Imad eAbout, Petros ePapagerakis   +5 more
doaj   +1 more source