Results 91 to 100 of about 7,133 (255)

Morphological alterations in the dentition of type I diabetes mellitus patients

Journal of Pharmacy and Bioallied Sciences, 2014
Introduction: Type 1 diabetes mellitus (DM) is an endocrine disorder that occurs commonly in an age group, where the development of primary and permanent dentition takes place. As altered endocrine functions may affect the shape and size of teeth leading
Andamuthu Yamunadevi, Praveen S Basandi, G S Madhushankari, Mandana Donoghue, Alur Manjunath, Manickam Selvamani, H K Puneeth   +6 more
doaj   +1 more source

Optineurin Cooperates With NRF2 to Regulate Tooth Root Morphogenesis by Controlling Mitochondrial Dynamics and Apoptosis

Cell Proliferation, Volume 58, Issue 5, May 2025.
OPTN interacts with NRF2 to facilitate the AKT/DRP1‐mediated regulation of mitochondrial fission in the cytoplasm of SCAPs, promoting tooth root mineralisation. Additionally, OPTN maintains NRF2's nuclear translocation, enhancing the transcriptional regulation of downstream BCL2, ultimately leading to the inhibition apoptosis in SCAPs and regulate ...
Haojie Liu, Xinyu Zhang, Xiao Ge, ChingCho Hsu, Yan Wang, Simai Chen, Xingzhi Yan, Rongyao Xu, Junqing Ma, Shuyu Guo   +9 more
wiley   +1 more source

Environmental stimuli‐responsive hydrogels in endodontics: Advances and perspectives

International Endodontic Journal, Volume 58, Issue 5, Page 674-684, May 2025.
Abstract Stimuli‐responsive hydrogels are smart and functional materials that respond to various environmental stimuli, including temperature, light, magnetic field, pH, redox, enzymes and glucose. This responsiveness allows for the controlled release of therapeutic agents encapsulated within the hydrogels, enhancing treatment precision, improving ...
He Liu, Ya Shen
wiley   +1 more source

Epigenetic Regulation of Dental Follicle Stem Cells in Odontogenic Regeneration

Journal of Cellular and Molecular Medicine, Volume 29, Issue 9, May 2025.
ABSTRACT MicroRNAs (miRNAs) are short non‐coding RNAs essential for biological functions that control the process of translation of mRNA into protein. The discovery of miRNAs in mesenchymal stem cells (MSCs), especially in odontogenic tissues and dental follicles, has not been fully characterised.
Sibel Elif Gultekin, Leyla Arslan Bozdag, Margarete Odenthal, Hans‐Peter Dienes   +3 more
wiley   +1 more source

Growth hormone receptor and insulin-like growth factor-I immunoreactivity in osteoclast-like cells during tooth eruption in the toothless (Osteopetrotic) rat following treatment with colony-stimulating factor-1 [PDF]

, 2003
In the toothless (tl/tl) osteopetrotic rat, teeth form but fail to erupt. Treatment of tl/tl rats with colony-stimulating factor-1 (CSF-1) activates bone resorption by osteoclasts, permits tooth eruption, and up-regulates the immunoreactivity of bone ...
Marks, Sandy C., Symons, Anne L., Weerakoon, Arosha   +2 more
core   +1 more source

Evaluation of the Expression Levels of Endothelin-1 and its Receptor (ETAR) in Dental Lamina during Different Stages of Development of Human Fetal Teeth

پزشکی بالینی ابن سینا, 2021
Background and Objective: Due to the significant importance of the teeth in mastication, speech, and aesthetics, it is necessary to identify all involved genes in the tooth development. Therefore, this study aimed to evaluate the role of endothelin-1 and
Soussan Irani, Shohreh Alimohammadi, Tahmineh Najafian   +2 more
doaj  

Neurotrophins (NTs) and Neurotrophin Receptors (NTRs) as emerging therapeutic paradigm in head and neck tumors - A mini review

Journal of Indian Academy of Oral Medicine and Radiology, 2020
Cells of the human biological system emerge from various concerted processes of cell growth, differentiation, repair, and regeneration to a degree.
Thuckanickenpalayam Ragunathan Yoithapprabhunath, Krubakar RachelSarahVinodhini, Shanmugam Mohanapriya, Joseph Babu Susai Raj, Vasudevan Kalaiselvi, Ramadas Madhavan Nirmal   +5 more
doaj   +1 more source

Spatiotemporal Expression Patterns of Critical Genes Involved in FGF Signaling During Morphogenesis and Odontogenesis of Deciduous Molars in Miniature Pigs [PDF]

, 2021
Wenwen Guo, Xia Li, Ran Zhang, Lei Hu, Jiangyi Wang, Fu Wang, Jinsong Wang, Chunmei Zhang, Xiaoshan Wu, Songlin Wang   +9 more
openalex   +1 more source

X‐Linked Hypophosphataemia and Burosumab: A Systemic Disease With a New Treatment

Journal of Paediatrics and Child Health, Volume 61, Issue 5, Page 685-700, May 2025.
ABSTRACT X linked hypophosphataemia (XLH) is a systemic, chronic condition that significantly impairs quality of life. In XLH, a phosphate regulating endopeptidase homologue X‐linked (PHEX) gene mutation leads to excess fibroblast growth factor 23 (FGF23), causing hypophosphataemia and subsequent rickets, lower limb deformity, pain and other sequelae ...
Jessica L. Sandy, Andrew Biggin, Aris Siafarikas, Peter J. Simm, Christine P. Rodda, Craig F. Munns   +5 more
wiley   +1 more source

Collagenous bone matrix-induced endochondral ossification hemopoiesis. [PDF]

, 1976
Transplantation of collagenous matrix from the rat diaphyseal bone to subcutaneous sites resulted in new bone formation by an endochondral sequence. Functional bone marrow develops within the newly formed ossicle.
Anderson, WA, Reddi, AH
core