Results 111 to 120 of about 220,145 (361)
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
The Olfactory Tubercle Encodes Odor Valence in Behaving Mice
Journal of Neuroscience, 2015 Sensory information acquires meaning to adaptively guide behaviors. Despite odors mediating a number of vital behaviors, the components of the olfactory system responsible for assigning meaning to odors remain unclear.
Marie A. Gadziola +3 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
Gain Control and Sparse Representations in the Olfactory System of the Locust and Fly [PDF]
, 2010 The giant GABAergic neuron (GGN) is a single, paired, non-spiking neuron that arborizes extensively in the mushroom body (MB) of the locust (Leitch and Laurent, 1996), where it overlaps with the dendrites and the axons of Kenyon cells (KCs).
Papadopoulou, Maria
core +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Journal of Japan Association on Odor Environment, 2006 食品，飲料，化粧品，環境計測などの分野では，においを簡便かつ客観的に測定できるセンサーが要求されている．水晶振動子ガスセンサーはかおりの強さとセンサー感度に相関があり，簡便に多様なセンサーを製作することができるので，このセンサーの原理と製作方法を紹介する．水晶振動子ガスセンサーを応用して，複数の要素臭の混ざったにおいを記録し，記録したにおいを再生するにおい記録再生システムの実験について述べる．さらにニーズが見込まれるセンサーとして低濃度の硫化物を検出して識別する口臭センサー，ガス検知管と光学センサーを利用した悪臭センサーについても紹介する．
openaire +2 more sources
Odor Landscapes in Turbulent Environments [PDF]
, 2014 The olfactory system of male moths is exquisitely sensitive to pheromones emitted by females and transported in the environment by atmospheric turbulence.
A. Celani, E. Villermaux, M. Vergassola
semanticscholar +1 more source
Odor Recognition and Segmentation By Coupled Olfactory Bulb and Cortical Networks [PDF]
, 1999 We present a model of a coupled system of the olfactory bulb and cortex. Odor inputs to the epithelium are transformed to oscillatory bulbar activities. The cortex recognizes the odor by resonating to the bulbar oscillating pattern when the amplitude and
Odor Recognition +2 more
core
Neural Circuit Dynamics and Ensemble Coding in the Locust and Fruit Fly Olfactory System [PDF]
, 2007 Raw sensory information is usually processed and reformatted by an organism’s brain to carry out tasks like identification, discrimination, tracking and storage.
Jayaraman, Vivek
core +1 more source
Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source