Results 81 to 90 of about 372,932 (302)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Evaluation of Blood Odor Signatures from Cadaveric Origin

Separations
Blood is a key biological specimen in forensic analysis for both living and deceased individuals, playing a crucial role in drug testing, blood typing, DNA analysis, and bloodstain pattern examination.
Lakshmi Reddi, Rex Johnson, Kerry K. Gilbert, Paola A. Prada-Tiedemann   +3 more
doaj   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

The Effectiveness of Potassium Permanganate in Oxidizing Hydrogen Sulfide and in Aiding Mechanical Dewatering of Pulp and Paper Industry Sludges [PDF]

, 1983
Introduction Odorous compounds have long been a significant problem faced by mills treating their own wastewater. This problem can be compounded when mechanical dewatering equipment is used to process primary and secondary sludges.
Rathfon, Russell
core   +1 more source

Segregation of odor identity and intensity during odor discrimination in Drosophila mushroom body [PDF]

, 2007
Molecular and cellular studies have begun to unravel a neurobiological basis of olfactory processing, which appears conserved among vertebrate and invertebrate species.
Shouzhen Xia, Tim Tully, Barry Dickson, Wilson, Ache, Shepherd, Linster, Shimshek, L&apos, Kelliher, Kadohisa, Devaud, Hildebrand, Ronnett, Mayford, Dubnau, Gomez-Diaz, Gottfried, Savic, Barkai, Quinlan, Connolly, de Belle, McGuire, Dubnau, Wang, Wang, Zou, Zou, Illig, Stopfer, Carlson, Tully, Boynton, Dura, Borst, Dudai, Kitamoto, Kalidas, Banerjee, Zars, Heimbeck, Stocker, Kulkarni, Ma, Chen, Levin, Margulies, Bargmann, Lin, Bargmann, Wang, Wang, Livingstone, Zeki, Schreiner, Tully, Chiang, McBride, Ito, Truman   +60 more
core   +2 more sources

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source

An analysis of food-economy companies’ environmental behaviour in North-East Hungary [PDF]

After outlining environmental problems regarding food-economy2 companies and clarifying the concept of environmental behaviour, I will present the results of my questionnaire survey which focussed on food-economy companies in the Northern Great Plain ...
Odor, Kinga
core   +1 more source

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub, Michele K. York, Roseanne Dobkin, Anuprita R. Nair, Ryan Kurth, David‐Erick Lafontant, Chelsea Caspell‐Garcia, Roy N. Alcalay, Ethan G. Brown, Lana M. Chahine, Christopher Coffey, Tatiana Foroud, Douglas Galasko, Karl Kieburtz, Kenneth Marek, Kalpana Merchant, Brit Mollenhauer, Kathleen L. Poston, Andrew Siderowf, Cristina Simonet, Tanya Simuni, Caroline M. Tanner, Thomas F. Tropea, Aleksandar Videnovic, The Parkinson's Progression Markers Initiative   +24 more
wiley   +1 more source

Towards Odor-Sensitive Mobile Robots [PDF]

, 2018
J. Monroy, J. Gonzalez-Jimenez, "Towards Odor-Sensitive Mobile Robots", Electronic Nose Technologies and Advances in Machine Olfaction, IGI Global, pp. 244--263, 2018, doi:10.4018/978-1-5225-3862-2.ch012 Versión preprint, con permiso del editorOut of ...
Gonzalez-Jimenez, Antonio Javier, Monroy, Javier   +1 more
core