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Odorant‐Binding Proteins: Expression and Function
Annals of the New York Academy of Sciences, 1998ABSTRACT: Odorant‐binding proteins (OBPs) are a major constituent of the aqueous perireceptor compartment in vertebrates and in insects. Although different in primary structure, they are supposed to serve similar functions in both animal groups: (i) OBPs may act as solubilizers and carriers of the lipophilic odorants in the aqueous mucus or sensillum ...
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Conformational Isomers of Insect Odorant-Binding Proteins
Archives of Biochemistry and Biophysics, 2002We have identified and cloned the cDNAs encoding odorant-binding proteins (OBPs) from the large black chafer, Holotrichia parallela, and the yellowish elongate chafer, Heptophylla picea. Each species possess two OBPs, the proteins migrating faster in native gels (OBP1) showed high amino acid identity (>88%) to previously identified pheromone-binding ...
Zhang, Deyu, Walter Soares, Leal
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Mechanistic events underlying odorant binding protein chemoreception
Proteins: Structure, Function, and Bioinformatics, 2007AbstractOdorant binding proteins (OBP's) are small hydrophilic proteins, belonging to the lipocalin family dedicated to bind and transport small hydrophobic ligands. Despite many works, the mechanism of ligand binding, together with the functional role of these proteins remains a topic of debate and little is known at the atomic level. The present work
Golebiowski, Jérôme +3 more
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Subtypes of odorant‐binding proteins
European Journal of Biochemistry, 1998Odorant‐binding proteins (OBP) in the mucus of the olfactory epithelium are thought to transfer the hydrophobic odorous compounds through the aqueous barrier towards the chemo‐sensory cells. To evaluate their binding properties, two distinct OBP subtypes of the rat were expressed as N‐terminal His‐tagged fusion proteins in Escherichia coli, thus ...
Lobel D +4 more
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Novel canine odorant binding proteins
2022La présente invention concerne l'utilisation d'une séquence choisie parmi Seq ID No 3, Seq ID No 1, Seq ID No 2, Seq ID No 4, Seq ID No 5, Seq ID No 6, Seq ID No 7, Seq ID No 8, et des variants fonctionnels correspondants, en tant que protéine de liaison odorante (OBP).
Glaz, Margot +4 more
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Structure and biotechnological applications of odorant-binding proteins
Applied Microbiology and Biotechnology, 2013Odorant-binding proteins (OBPs) are small soluble polypeptides found in sensory organs of vertebrates and insects as well as in secretory glands and are dedicated to detection and release of chemical stimuli. OBPs of vertebrates belong to the family of lipocalin proteins, while those of insects are folded into α-helical domains.
Pelosi, Paolo +4 more
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Biosensors Based on Odorant Binding Proteins
2014Both the sensillary lymph of insects and the nasal mucus of vertebrates contain large amounts of small soluble proteins, odorant-binding proteins that specifically and reversibly bind odors and pheromones. Proteins from different sources have affinities toward a wide range of compounds with different sizes and shapes.
Persaud, Krishna C, Tuccori, Elena
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