Results 51 to 60 of about 18,555 (215)

Biochemical and Genetic Studies of UBR3, a Ubiquitin Ligase with a Function in Olfactory and Other Sensory Systems [PDF]

, 2007
Our previous work identified E3 ubiquitin ligases, termed UBR1-UBR7, that contain the ~70-residue UBR box, a motif important for the targeting of N-end rule substrates.
Hellweg, Rainer, Hörtnagl, Heidi, Kwon, Yong Tae, Sohr, Reinhard, Tasaki, Takafumi, Varshavsky, Alexander, Xia, Zanxian   +6 more
core   +1 more source

Organization and function of Drosophila odorant binding proteins

eLife, 2016
Odorant binding proteins (Obps) are remarkable in their number, diversity, and abundance, yet their role in olfactory coding remains unclear. They are widely believed to be required for transporting hydrophobic odorants through an aqueous lymph to ...
Nikki K Larter, Jennifer S Sun, John R Carlson   +2 more
doaj   +1 more source

Computational exploration of molecular receptive fields in the olfactory bulb reveals a glomerulus-centric chemical map [PDF]

, 2020
© The Author(s) 2020. This article is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.Progress in olfactory research is currently hampered by ...
A Nagashima, A. Yablonka, B Malnic, BA Johnson, DB Chklovskii, DB Turner, EI Knudsen, ER Soucy, Eva M. Neuhaus, F Pedregosa, H Matsumoto, H Saito, IV Tetko, J Li, J Soelter, JH Kaas, JH Kaas, JL Pluznick, K Grill-Spector, K Miyamichi, K Mori, KJ Ressler, L Belluscio, L Ma, M Meister, M Schmuker, O Baud, PI Ezeh, R Haddad, R Vassar, R Vincis, RC Araneda, S Conzelmann, S Gabler, S Katada, SE Repicky, SL Sullivan, SM Boyle, T Abaffy, T Bozza, T Bozza, T Bozza, T Sato, TJ Imig, TP Hettinger, V Consonni, Verena Bautze, W Härdle, X Grosmaitre, Y Oka, Z Peterlin   +50 more
core   +2 more sources

Identification of the Plasticity-Relevant Fucose-α(1−2)-Galactose Proteome from the Mouse Olfactory Bulb [PDF]

, 2009
Fucose-α(1−2)-galactose [Fucα(1−2)Gal] sugars have been implicated in the molecular mechanisms that underlie neuronal development, learning, and memory. However, an understanding of their precise roles has been hampered by a lack of information regarding
Domino, Steven E., Ficarro, Scott B., Hsieh-Wilson, Linda C., Krishnamurthy, Chithra, Murrey, Heather E., Peters, Eric C.   +5 more
core   +4 more sources

Antennal Transcriptome Analysis of the Chemosensory Gene Families From Trichoptera and Basal Lepidoptera

Frontiers in Physiology, 2018
The chemosensory gene families of insects encode proteins that are crucial for host location, mate finding, oviposition, and avoidance behaviors. The insect peripheral chemosensory system comprises odorant receptors (ORs), gustatory receptors (GRs ...
Jothi Kumar Yuvaraj, Martin N. Andersson, Dan-Dan Zhang, Christer Löfstedt   +3 more
doaj   +1 more source

Enzymatic Basis for the Oxidative Branch of Aromatic Amino Acid Fermentation Leading to p‐cresol Formation

Advanced Science, EarlyView.
In anaerobic bacteria, tyrosine serves as an electron donor in the oxidative Stickland fermentation branch, generating p‐hydroxyphenylacetate, ATP and reduced ferredoxin for decarboxylation into p‐cresol. ABSTRACT The phenolic metabolite p‐cresol is a byproduct of tyrosine fermentation by certain strictly anaerobic bacteria, including the human gut ...
Li Jiang, Yifeng Wei, Xumei Liu, Dazhi Liu, Zhenyu Liu, Yang Tong, Jinyu Yin, Ankanahalli N. Nanjaraj Urs, Meining Xing, Mark A. Harrison, Chuyuan Zhang, Sheng Yang, Yunzi Luo, Ee Lui Ang, Huimin Zhao, Yan Zhang   +15 more
wiley   +1 more source

Insertion of T4-lysozyme (T4L) can be a useful tool for studying olfactory-related GPCRs. [PDF]

, 2012
The detergents used to solubilize GPCRs can make crystal growth the rate-limiting step in determining their structure. The Kobilka laboratory showed that insertion of T4-lysozyme (T4L) in the 3rd intracellular loop is a promising strategy towards ...
Baaske, Baud, Brian L. Cook, Cherezov, Chien, Christoph J. Wienken, Cook, Cook, Corin, Corin, Dahoun, Dieter Braun, Duhr, Garavito, Gimelbrant, Gimelbrant, Greenfield, Hanson, Horst Pick, Horst Vogel, Jaakola, Jacquier, Jayadev, Karolina Corin, Katada, Loll, Lu, Lu, McClintock, Philipp Baaske, Pick, Rasmussen, Ren, Rodriguez, Shimamura, Shirokova, Shuguang Zhang, Spehr, Spehr, Stefan Duhr, Wallin, Warne, Wienken, Wu   +43 more
core   +1 more source

Genomic content of chemosensory genes correlates with host range in wood-boring beetles (Dendroctonus ponderosae, Agrilus planipennis, and Anoplophora glabripennis)

BMC Genomics, 2019
Background Olfaction and gustation underlie behaviors that are crucial for insect fitness, such as host and mate selection. The detection of semiochemicals is mediated via proteins from large and rapidly evolving chemosensory gene families; however, the ...
Martin N. Andersson, Christopher I. Keeling, Robert F. Mitchell   +2 more
doaj   +1 more source

Microbial Odorant Detection Guides Drosophila Parasitoids Seeking Hosts in Fermenting Fruits

Advanced Science, EarlyView.
Yeast microbes in fermenting fruits attract both host flies and their parasitoid wasps. Female Leptopilina boulardi detect yeast‐emitted ethyl esters via two olfactory receptors, LbouOR167 and LbouOR136. A conserved residue, Leu159, is critical for binding these compounds, enabling female wasps to locate host‐rich habitats.
Yueqi Lu, Lan Pang, Wenqi Shi, Ting Feng, Zhi Dong, Yifeng Sheng, Sicong Zhou, Longtao Yu, Hao Guo, Ying Wang, Jiani Chen, Jianhua Huang   +11 more
wiley   +1 more source

Comparative proteomic profiling reveals molecular characteristics associated with oogenesis and oocyte maturation during ovarian development of Bactrocera dorsalis (Hendel) [PDF]

, 2017
Time-dependent expression of proteins in ovary is important to understand oogenesis in insects. Here, we profiled the proteomes of developing ovaries from Bactrocera dorsalis (Hendel) to obtain information about ovarian development with particular ...
Wei, Dong, Li, Ran, Zhang, Meng-Yi, Liu, Yu-Wei, Zhang, Zheng, Smagghe, Guy, Wang, Jin-Jun   +6 more
core   +1 more source