Putative ligand binding sites of two functionally characterized bark beetle odorant receptors
Background: Bark beetles are major pests of conifer forests, and their behavior is primarily mediated via olfaction. Targeting the odorant receptors (ORs) may thus provide avenues towards improved pest control.
Andersson, Martin N., +12 more
core +1 more source
Requirement for Slit-1 and Robo-2 in zonal segregation of olfactory sensory neuron axons in the main olfactory bulb [PDF]
The formation of precise stereotypic connections in sensory systems is critical for the ability to detect and process signals from the environment. In the olfactory system, olfactory sensory neurons (OSNs) project axons to spatially defined glomeruli ...
Andrews, W +4 more
core +1 more source
The porcine odorant-binding protein as molecular probe for benzene detection. [PDF]
In recent years, air pollution has been a subject of great scientific and public interests for the strong impact on human health. Air pollution is due to the presence in the atmosphere of polluting substances, such as carbon monoxide, sulfur and nitrogen
Alessandro Capo +4 more
doaj +1 more source
Gene content evolution in the arthropods [PDF]
Arthropods comprise the largest and most diverse phylum on Earth and play vital roles in nearly every ecosystem. Their diversity stems in part from variations on a conserved body plan, resulting from and recorded in adaptive changes in the genome ...
Anstead, Clare A. +78 more
core +1 more source
Wake Up and Smell the Infected Bees: Volatile Cues of Vairimorpha Infection in Honey Bees
Infection can modify host volatile emissions, yet effects in adult honey bees remain unexplored. Using dynamic headspace sampling and GC × GC–MS, we show that Vairimorpha spp. infection significantly alters the volatile profile of adult worker honey bees over a 14‐day time series, producing stage‐specific shifts in multivariate odour structure.
Ayman Asiri +2 more
wiley +1 more source
Identification of the Plasticity-Relevant Fucose-α(1−2)-Galactose Proteome from the Mouse Olfactory Bulb [PDF]
Fucose-α(1−2)-galactose [Fucα(1−2)Gal] sugars have been implicated in the molecular mechanisms that underlie neuronal development, learning, and memory. However, an understanding of their precise roles has been hampered by a lack of information regarding
Domino, Steven E. +5 more
core +1 more source
Cilia in Nervous System Development, Function, and Disease
Cilia are evolutionarily conserved organelles that function as essential sensory and motility platforms in the nervous system. This review outlines key cilia‐dependent signaling pathways and their roles in neural development and function. Furthermore, it highlights how ciliary dysfunction can lead to a variety of neurological disorders, known as ...
Qingchao Li, Anqi Zhang, Ting Song
wiley +1 more source
Insertion of T4-lysozyme (T4L) can be a useful tool for studying olfactory-related GPCRs. [PDF]
The detergents used to solubilize GPCRs can make crystal growth the rate-limiting step in determining their structure. The Kobilka laboratory showed that insertion of T4-lysozyme (T4L) in the 3rd intracellular loop is a promising strategy towards ...
Baaske +43 more
core +1 more source
GRKs and arrestins: Nomenclature and functions in GPCR‐dependent and ‐independent signalling
G protein‐coupled receptor (GPCR) kinases (GRKs) and arrestins play a critical role in the regulation of GPCR signalling. Historic names of mammalian GRKs were replaced by systematic ones in the 1990s; however, both kinds of names are currently in use for mammalian arrestins.
Vsevolod V. Gurevich
wiley +1 more source
Humidity response depends on the small soluble protein Obp59a in Drosophila
Hygrosensation is an essential sensory modality that is used to find sources of moisture. Hygroreception allows animals to avoid desiccation, an existential threat that is increasing with climate change.
Jennifer S Sun +5 more
doaj +1 more source

