Results 101 to 110 of about 2,668,755 (284)

Implantable Brain–Machine Interface for Olfactory Neural Regulation in Bioelectronic Nose: A Review

Sensory Neuroscience, EarlyView.
The olfactory Brain‐Machine Interface described in this paper bypasses damaged peripheral olfactory pathways by implanting stimulation electrodes in the olfactory bulb or higher‐order olfactory cortex, thereby forming a closed‐loop system that integrates signal acquisition, information decoding, and cortical integration.
Chen Wang, Chunmei Tu, Jian Liu, Fangyuan Zhu, Hongjie Du, Zhaoze Yang, Chengcheng Liu, Xuening Zhao   +7 more
wiley   +1 more source

A purely bioinformatic pipeline for the prediction of mammalian odorant receptor gene enhancers

BMC Bioinformatics, 2019
Background In most mammals, a vast array of genes coding for chemosensory receptors mediates olfaction. Odorant receptor (OR) genes generally constitute the largest multifamily (> 1100 intact members in the mouse).
Andrea Degl’Innocenti, Gabriella Meloni, Barbara Mazzolai, Gianni Ciofani   +3 more
doaj   +1 more source

The Mouse Eugenol Odorant Receptor : Structural and Functional Plasticity of a Broadly Tuned Odorant Binding Pocket

, 2010
Molecular interactions of odorants with their olfactory receptors (ORs) are of central importance for the ability of the mammalian olfactory system to detect and discriminate a vast variety of odors with a limited set of receptors.
Etter, S., Schwede, Torsten, Pick, H. M., Spreafico, Morena, Baud, O., Baud, Olivia, Horst Vogel, Bordoli, Lorenza, Spreafico, M., Olivia Baud, Vogel, H., Pick, Horst, Sylvain Etter, Horst Pick, Etter, Sylvain, Morena Spreafico, Torsten Schwede, Schwede, T., Vogel, Horst, Bordoli, L., Lorenza Bordoli   +20 more
core   +1 more source

Diving Deeper Into Mechanisms of Acrylamide‐Induced Toxicity: RNA Sequencing Reveals Transcriptomic Alteration and Retrotransposon Expression in Drosophila melanogaster

Environmental Toxicology, EarlyView.
ABSTRACT Given the inevitability of human and animal exposure to acrylamide, there is increasing concern regarding its potential health risks. While a number of molecular mechanisms have been proposed, the complexity of acrylamide toxicological pathways and interactions remains incompletely characterized.
Oluwabukola Mary Farodoye, Titilayomi Ayomide Otenaike, Daniela Moreira Mombach, Monica Medeiros Silva, Amos Olalekan Abolaji, Elgion Lucio Da Silva Loreto   +5 more
wiley   +1 more source

The Mouse Eugenol Odorant Receptor: Structural and Functional Plasticity of a Broadly Tuned Odorant Binding Pocket

, 2016
Molecular interactions of odorants with their olfactory receptors (ORs) are of central importance for the ability of the mammalian olfactory system to detect and discriminate a vast variety of odors with a limited set of receptors.
Horst Vogel (208939), Horst Pick (1844257), Torsten Schwede (61260), Morena Spreafico (2233216), Olivia Baud (2233213), Sylvain Etter (2233219), Lorenza Bordoli (2233210)   +6 more
core   +1 more source

Adaptation of the invasive pest Drosophila suzukii to a specialized nutritional niche

Insect Science, EarlyView.
Unlike most Drosophila larvae that feed on spoiled food, Drosophila suzukii larvae thrive on ripening fruits and consequently face a low‐protein, high‐carbohydrate nutritional challenge. Comparisons of growth among D. suzukii, D. biarmipes, and D. melanogaster larvae across diets with varying protein‐to‐carbohydrate ratios demonstrate that D.
Yan Hou, Ying Zhen
wiley   +1 more source

Drugs that act on both G protein‐coupled receptors (GPCRs) and kinases: potentiation of effects, side effects and general aspects of drug pleiotropy

British Journal of Pharmacology, EarlyView.
Abstract Background A drug designed for a specific target often interacts with multiple targets, either unintentionally or as part of its intended mechanism of action. This has been called pharmacological pleiotropy or polypharmacology. There are key endogenous ligands such as ATP, GABA and glutamate that act on various proteins in humans. Furthermore,
Hampus Ljunggren, Aleksandr Sokolov, Flavio Ballante, Robert Fredriksson, Francisco Lagunas‐Rangel, Alexander S. Hauser, Stefan Knapp, Jörgen Jonsson, Helgi B. Schiöth   +8 more
wiley   +1 more source

Functional Characterization of the Odorant Receptor 51E2 in Human Melanocytes*

Journal of Biological Chemistry, 2016
Olfactory receptors, which belong to the family of G-protein-coupled receptors, are found to be ectopically expressed in non-sensory tissues mediating a variety of cellular functions.
L. Gelis, Nikolina Jovancevic, Sophie Veitinger, Bhubaneswar Mandal, Hans‐Dieter Arndt, E. Neuhaus, H. Hatt   +6 more
semanticscholar   +1 more source

Development and Reproduction of Nesidiocoris tenuis Reuter (Heteroptera: Miridae): The Effect of Temperature, Origin and Food

Entomologia Experimentalis et Applicata, EarlyView.
Nymphal development took longer at 25°C than 30°C, and the Greek N. tenuis population developed more slowly than the commercial population. Nymphs clearly preferred E. kuehniella eggs over Artemia sp. cysts when both were offered equally. Egg production increased at 30°C, while female longevity declined.
Eleni Yiacoumi, Sofoklis Flouris, Dimitrios Fytilis, Maria Gkamsizi, Nikos A. Kouloussis, Dimitrios S. Koveos   +5 more
wiley   +1 more source

The Odorant Receptor-Dependent Role of Olfactory Marker Protein in Olfactory Receptor Neurons

Journal of Neuroscience, 2016
Olfactory receptor neurons (ORNs) in the nasal cavity detect and transduce odorants into action potentials to be conveyed to the olfactory bulb. Odorants are delivered to ORNs via the inhaled air at breathing frequencies that can vary from 2 to 10 Hz in ...
M. Dibattista, J. Reisert
semanticscholar   +1 more source