Results 81 to 90 of about 1,252,084 (241)

Decoding the olfactory map through targeted transcriptomics links murine olfactory receptors to glomeruli

open access: yesNature Communications, 2022
Targeted spatial transcriptomics mapped olfactory receptor mRNAs to sections of the murine olfactory bulb to generate an interactive, statistical, 3D model of glomeruli locations and identify an ultra-sensitive receptor-odorant relationship.
Kevin W. Zhu   +6 more
doaj   +1 more source

The Audiologic and Otolaryngologic Phenotype in WHIM Syndrome

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective WHIM syndrome (warts, hypogammaglobulinemia, infections, and myelokathexis syndrome) is an ultra‐rare primary immunodeficiency disease caused by autosomal dominant hyperfunctional mutations in the chemokine receptor CXCR4. Otolaryngologists are frequently consulted to evaluate WHIM patients because of recurrent acute ear and sinus ...
Christopher K. Zalewski   +7 more
wiley   +1 more source

Odor coding by a mammalian receptor repertoire [PDF]

open access: yesNeuroscience Research, 2009
Identification of mammalian olfactory receptor agonists enables development of a predictive model of receptor activation.
Harumi, Saito   +4 more
openaire   +2 more sources

Rapid encoding and perception of novel odors in the rat. [PDF]

open access: yesPLoS Biology, 2008
To gain insight into which parameters of neural activity are important in shaping the perception of odors, we combined a behavioral measure of odor perception with optical imaging of odor representations at the level of receptor neuron input to the rat ...
Daniel W Wesson   +3 more
doaj   +1 more source

Effects of Minority Status on Sensory Outcomes, Cognition, and Depression

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To evaluate the association between minority status and sensory function, sleep quality, depressive symptoms, and cognitive performance in an aging population. Study Design Prospective, cross‐sectional study. Setting Participants were recruited from the Department of Otolaryngology and the Center for Cognitive Neuroscience and Aging ...
Ivette Cejas   +9 more
wiley   +1 more source

Coding Odorant Concentration through Activation Timing between the Medial and Lateral Olfactory Bulb

open access: yesCell Reports, 2012
In mammals, each olfactory bulb (OB) contains a pair of mirror-symmetric glomerular maps organized to reflect odorant receptor identity. The functional implication of maintaining these symmetric medial-lateral maps within each OB remains unclear.
Zhishang Zhou, Leonardo Belluscio
doaj   +1 more source

Theoretical Analysis of Androstenone Adsorption on Chimpanzee and Gorilla Olfactory Receptors (G‐Protein): Statistical Physics Modeling, Molecular Docking Simulation, and Thermodynamic Investigation

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT An advanced theory based on statistical physics was applied to microscopically investigate androstenone adsorption and its relationship with olfactory perception in chimpanzees and gorillas. For this purpose, dose–response curves of androstenone on olfactory receptors of chimpanzee OR7D4 and gorilla OR7D4 were analyzed by statistical physics ...
Ismahene Ben Khemis   +8 more
wiley   +1 more source

The Olfactory Nervous System Of Terrestrial And Aquatic Vertebrates [PDF]

open access: yes, 2011
Animals in their natural milieu are surrounded by odors. These odors are rich source of information, and are perceived by sophisticated olfactory systems, that have evolved over time.
Ashiq Hussain
core  

A purely bioinformatic pipeline for the prediction of mammalian odorant receptor gene enhancers

open access: yesBMC Bioinformatics, 2019
Background In most mammals, a vast array of genes coding for chemosensory receptors mediates olfaction. Odorant receptor (OR) genes generally constitute the largest multifamily (> 1100 intact members in the mouse).
Andrea Degl’Innocenti   +3 more
doaj   +1 more source

Multimodal targets of (‐)‐α‐thujone mediating avoidance behavior of a stored‐products pest, Tribolium castaneum, in response to irritant stimuli

open access: yesPest Management Science, EarlyView.
We identified four kinds of target molecules against (‐)‐α‐thujone associating avoidance behavior in Tribolium castaneum, indicating multimodality. Abstract BACKGROUND The reciprocal evolutionary processes among phytophagous insects and host plants involve host shift in the herbivorous insects in response to defense chemicals, such as plant‐derived ...
Kenji Shimomura   +4 more
wiley   +1 more source

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