Results 71 to 80 of about 2,668,755 (284)

An Olfactory Receptor Pseudogene whose Function emerged in Humans

open access: yes, 2007
Human olfactory receptor, hOR17-210, is identified as a pseudogene in the human genome. Experimental data has shown however, that the gene product of cloned hOR17-210 cDNA was able to bind an odorant-binding protein and is narrowly tuned for excitation ...
Gautam Bahl   +6 more
core   +1 more source

Expanding the olfactory code by in silico decoding of odor-receptor chemical space

open access: yeseLife, 2013
Coding of information in the peripheral olfactory system depends on two fundamental factors: interaction of individual odors with subsets of the odorant receptor repertoire and mode of signaling that an individual receptor-odor interaction elicits ...
Sean Michael Boyle   +2 more
doaj   +1 more source

The origin of the odorant receptor gene family in insects

open access: yesbioRxiv, 2018
The sense of smell enables the detection and discrimination of airborne chemicals via chemosensory receptors that have evolved independently multiple times throughout the tree of life.
Philipp Brand   +6 more
semanticscholar   +1 more source

Computational investigation of aphid odorant receptor structure and binding function

open access: yes, 2022
Odorant receptors (OR) play a critical role in signal transduction and olfactory recognition in insects. Unfortunately, insect ORs are difficult to express and purify, and limited structural data are available.
Oldham, N.   +14 more
core   +1 more source

Phenylthiophenecarboxamide antagonists of the olfactory receptor co-receptor subunit from a mosquito. [PDF]

open access: yesPLoS ONE, 2013
Insects detect environmental chemicals using chemosensory receptors, such as the ORs, a family of odorant-gated ion channels. Insect ORs are multimeric complexes of unknown stoichiometry, formed by a common subunit (the odorant receptor co-receptor ...
Sisi Chen, Charles W Luetje
doaj   +1 more source

Modulation of the combinatorial code of odorant receptor response patterns in odorant mixtures

open access: yesbioRxiv, 2019
The perception of odors relies on combinatorial codes consisting of odorant receptor (OR) response patterns to encode odor identity. The modulation of these patterns by odorant interactions at ORs potentially explains several olfactory phenomena: mixture
Claire A. de March   +5 more
semanticscholar   +1 more source

Coding of Odors by a Receptor Repertoire [PDF]

open access: yesCell, 2006
We provide a systematic analysis of how odor quality, quantity, and duration are encoded by the odorant receptor repertoire of the Drosophila antenna. We test the receptors with a panel of over 100 odors and find that strong responses are sparse, with response density dependent on chemical class.
Hallem, Elissa A., Carlson, John R.
openaire   +2 more sources

Combinatorial Receptor Codes for Odors [PDF]

open access: yesCell, 1999
The discriminatory capacity of the mammalian olfactory system is such that thousands of volatile chemicals are perceived as having distinct odors. Here we used a combination of calcium imaging and single-cell RT-PCR to identify odorant receptors (ORs) for odorants with related structures but varied odors.
Malnic, Bettina   +3 more
openaire   +3 more sources

Recent Advances in Laser‐Induced Graphene‐Based Gas Sensors: From Sensing Mechanisms to Biomedical Applications

open access: yesAdvanced Science, EarlyView.
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Md Abu Sayeed Biswas   +6 more
wiley   +1 more source

Microbial Odorant Detection Guides Drosophila Parasitoids Seeking Hosts in Fermenting Fruits

open access: yesAdvanced Science, EarlyView.
Yeast microbes in fermenting fruits attract both host flies and their parasitoid wasps. Female Leptopilina boulardi detect yeast‐emitted ethyl esters via two olfactory receptors, LbouOR167 and LbouOR136. A conserved residue, Leu159, is critical for binding these compounds, enabling female wasps to locate host‐rich habitats.
Yueqi Lu   +11 more
wiley   +1 more source

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