Results 61 to 70 of about 1,252,084 (241)

Combinatorial Receptor Codes for Odors [PDF]

Cell, 1999
The discriminatory capacity of the mammalian olfactory system is such that thousands of volatile chemicals are perceived as having distinct odors. Here we used a combination of calcium imaging and single-cell RT-PCR to identify odorant receptors (ORs) for odorants with related structures but varied odors.
Malnic, Bettina, Hirono, Junzo, Sato, Takaaki, Buck, Linda B   +3 more
openaire   +3 more sources

Asymmetric Evolution of Antennal Cell Types Underlies a Derived Ammonia‐Sensing Logic for Ecological Adaptation in Bactrocera dorsalis

Advanced Science, EarlyView.
Comparative antennal single‐nucleus transcriptomics reveals cell‐type‐dependent transcriptomic divergence in Bactrocera dorsalis, with similar structural cells but divergent sensory neurons. This neuronal diversification is associated with a distinct ammonia‐sensing pathway, linking female attraction to bird‐dropping‐associated cues with nutritional ...
Wei Liu, Shuai Zhang, Jie Zhang, Zhen Tian, Yuanbo Xue, Ling Yang, Jun Xu, Guirong Wang   +7 more
wiley   +1 more source

Lost and Found: Is Olfactory Recovery More Promising After COVID‐19 Than Other Causes, Even 2 Years Later?

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Olfactory dysfunction is a hallmark feature of COVID‐19, yet the potential for recovery with long‐standing COVID‐19‐related smell loss (CRSL) remains uncertain, particularly when treatment is initiated years later. This study evaluated olfactory outcomes in patients with CRSL compared with non‐COVID‐19‐related smell loss (non‐CRSL),
John W. Hunsicker, Mabel Berg, Nicolaus Knight, Jessica W. Grayson, Bradford A. Woodworth, Justin H. Turner, Do‐Yeon Cho   +6 more
wiley   +1 more source

Bioluminescence Resonance Energy Transfer Reveals the Adrenocorticotropin (ACTH)-Induced Conformational Change of the Activated ACTH Receptor Complex in Living Cells [PDF]

, 2011
Bioluminescence resonance energy transfer analysis is used to study the interaction between melanocortin 2 receptor (MC2R) accessory protein and the MC2R and provides evidence for protein kinase A-dependent conformational changes in the receptor complex ...
Adrian J. L. Clark, Szidonya, L, Laszlo Szidonya, Cooray, SN, Mazhar, K, Teng-Teng Chung, Clark, AJ, Khansa Mazhar, Chung, TT, Sadani N. Cooray   +9 more
core   +1 more source

Kinetics of Odorant Recognition with a Graphene-Based Olfactory Receptor Mimicry

Chemosensors, 2022
Malaria vector mosquito species rely on a handful of specific pheromones for mating; one of them, sulcatone (6-methyl-5-hepten-2-one), is also found in human exudation.
Caroline Bonazza, Klaus Bonazza
doaj   +1 more source

Requirement for Slit-1 and Robo-2 in zonal segregation of olfactory sensory neuron axons in the main olfactory bulb [PDF]

, 2007
The formation of precise stereotypic connections in sensory systems is critical for the ability to detect and process signals from the environment. In the olfactory system, olfactory sensory neurons (OSNs) project axons to spatially defined glomeruli ...
Cloutier, J-F, Cho, JH, Parnavelas, J, Andrews, W, Lépine, M   +4 more
core  

Odorant Concentration Differentiator for Intermittent Olfactory Signals [PDF]

, 2014
Animals need to discriminate differences in spatiotemporally distributed sensory signals in terms of quality as well as quantity for generating adaptive behavior.
Namiki Shigehiro, Haupt Stephan Shuichi, Kazawa Tomoki, Sakurai Takeshi, Uchino Keiro, Fujiwara Terufumi, Yamagata Tomoko, Kanzaki Ryohei, Fukushima Ryota   +8 more
core   +1 more source

Odorant-binding protein expression in dMPPED^KO flies.

, 2023
Odorant-binding protein expression in dMPPEDKO flies.
Deepthi Mahishi (6494951), Vishnu Janardan (17020978), Swarna Srinivas (17020984), Sveta Chakrabarti (634821), Sanghita Banerjee (806014), Sandhya S. Visweswariah (10736916), Kriti Gupta (741894), Nishita Gogia (17020981)   +7 more
core   +1 more source

Associations Between Multiple Chemosensory Dysfunction and Cognition

International Forum of Allergy &Rhinology, EarlyView.
Key Points This study supports the association between chemosensory dysfunction and cognition. We introduce methods of assessing trigeminal function with the Medoc TSA‐II thermoprobe. Our results identify an association between subjective trigeminal dysfunction and cognition.
Michelle Yu, Stephanie M. Horton, Tiffany Chen, Shaun A. Nguyen, Zachary M. Soler, Rodney J. Schlosser   +5 more
wiley   +1 more source

Genetic elucidation of human hyperosmia to isovaleric acid.

PLoS Biology, 2007
The genetic basis of odorant-specific variations in human olfactory thresholds, and in particular of enhanced odorant sensitivity (hyperosmia), remains largely unknown.
Idan Menashe, Tatjana Abaffy, Yehudit Hasin, Sivan Goshen, Vered Yahalom, Charles W Luetje, Doron Lancet   +6 more
doaj   +1 more source