Results 41 to 50 of about 2,668,959 (274)

Expressing exogenous functional odorant receptors in cultured olfactory sensory neurons

open access: yesNeural Development, 2008
Background Olfactory discrimination depends on the large numbers of odorant receptor genes and differential ligand-receptor signaling among neurons expressing different receptors.
Fomina Alla F   +3 more
doaj   +1 more source

The Zonal Organization of Odorant Receptor Gene Choice in the Main Olfactory Epithelium of the Mouse.

open access: yesCell Reports, 2020
A mature olfactory sensory neuron (OSN) of the main olfactory epithelium (MOE) typically expresses one allele of one odorant receptor (OR) gene. It is widely thought that the great majority of the 1,141 intact mouse OR genes are expressed in one of four ...
Bolek Zapiec, P. Mombaerts
semanticscholar   +1 more source

An Olfactory Receptor Pseudogene whose Function emerged in Humans [PDF]

open access: yes, 2007
Human olfactory receptor, hOR17-210, is identified as a pseudogene in the human genome. Experimental data has shown however, that the gene product of cloned hOR17-210 cDNA was able to bind an odorant-binding protein and is narrowly tuned for excitation ...
Catherine Ronin   +6 more
core   +2 more sources

The Emergence of Insect Odorant Receptor-Based Biosensors

open access: yesBiosensors, 2020
The olfactory receptor neurons of insects and vertebrates are gated by odorant receptor (OR) proteins of which several members have been shown to exhibit remarkable sensitivity and selectivity towards volatile organic compounds of significant importance ...
J. Bohbot, S. Vernick
semanticscholar   +1 more source

Overlapping but distinct topology for zebrafish V2R-like olfactory receptors reminiscent of odorant receptor spatial expression zones

open access: yesBMC Genomics, 2018
Background The sense of smell is unrivaled in terms of molecular complexity of its input channels. Even zebrafish, a model vertebrate system in many research fields including olfaction, possesses several hundred different olfactory receptor genes ...
Gaurav Ahuja   +7 more
doaj   +1 more source

Rapid evolution of chemosensory receptor genes in a pair of sibling species of orchid bees (Apidae: Euglossini). [PDF]

open access: yes, 2015
BackgroundInsects rely more on chemical signals (semiochemicals) than on any other sensory modality to find, identify, and choose mates. In most insects, pheromone production is typically regulated through biosynthetic pathways, whereas pheromone sensory
Brand, Philipp   +5 more
core   +3 more sources

Mixture and concentration effects on odorant receptor response patterns in vivo.

open access: yesChemical Sensors, 2020
Natural odors are mixtures of volatile chemicals (odorants). Odors are encoded as responses of distinct subsets of the hundreds of odorant receptors and trace amine-associated receptors expressed monogenically by olfactory sensory neurons.
T. McClintock   +4 more
semanticscholar   +1 more source

Mammalian odorant receptor tuning breadth persists across distinct odorant panels. [PDF]

open access: yesPLoS ONE, 2017
The molecular receptive range (MRR) of a mammalian odorant receptor (OR) is the set of odorant structures that activate the OR, while the distribution of these odorant structures across odor space is the tuning breadth of the OR.
Devin Kepchia   +3 more
doaj   +1 more source

Putative ligand binding sites of two functionally characterized bark beetle odorant receptors

open access: yes, 2021
Background: Bark beetles are major pests of conifer forests, and their behavior is primarily mediated via olfaction. Targeting the odorant receptors (ORs) may thus provide avenues towards improved pest control.
Andersson, Martin N.,   +12 more
core   +1 more source

Structural Features of an OR37 Glomerulus: A Comparative Study

open access: yesFrontiers in Neuroanatomy, 2017
In the olfactory bulb (OB) a sophisticated neuronal network mediates the primary processing of sensory information and extensive investigations over the past decades have greatly improved our understanding of the morphology and neuronal organization of ...
Anna-Maria Maier   +2 more
doaj   +1 more source

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