BMC Genomics, 2019 Background Odorant receptor genes constitute the largest gene family in mammalian genomes and this family has been extensively studied in several species, but to date far less attention has been paid to the characterization of their mRNA 3′ untranslated ...
Mohamed Doulazmi +4 more
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Association of smoking behavior with an odorant receptor allele telomeric to the human major histocompatibility complex [PDF]
, 2008 Smoking behavior has been associated in two independent European cohorts with the most common Caucasian human leukocyte antigen (HLA) haplotype (A1-B8-DR3). We aimed to test whether polymorphic members of the two odorant receptor (OR) clusters within the
Yu CY +28 more
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Co-regulation of a large and rapidly evolving repertoire of odorant receptor genes
BMC Neuroscience, 2007 The olfactory system meets niche- and species-specific demands by an accelerated evolution of its odorant receptor repertoires. In this review, we describe evolutionary processes that have shaped olfactory and vomeronasal receptor gene families in ...
Lane Robert P, Kambere Marijo B
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Predicting olfactory receptor neuron responses from odorant structure [PDF]
, 2007 Background Olfactory receptors work at the interface between the chemical world of volatile molecules and the perception of scent in the brain. Their main purpose is to translate chemical space into information that can be processed by neural circuits ...
De Bruyne, Marien +11 more
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Expressing exogenous functional odorant receptors in cultured olfactory sensory neurons
Neural Development, 2008 Background Olfactory discrimination depends on the large numbers of odorant receptor genes and differential ligand-receptor signaling among neurons expressing different receptors.
Fomina Alla F +3 more
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Inhibition of insect olfactory behavior by an airborne antagonist of the insect odorant receptor co-receptor subunit. [PDF]
PLoS ONE, 2017 Response to volatile environmental chemosensory cues is essential for insect survival. The odorant receptor (OR) family is an important class of receptors that detects volatile molecules; guiding insects towards food, mates, and oviposition sites.
Devin Kepchia +4 more
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BMC Genomics, 2018 Background The sense of smell is unrivaled in terms of molecular complexity of its input channels. Even zebrafish, a model vertebrate system in many research fields including olfaction, possesses several hundred different olfactory receptor genes ...
Gaurav Ahuja +7 more
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A carboxylesterase, Esterase-6, modulates sensory physiological and behavioural response dynamics to pheromone in Drosophila [PDF]
, 2012 Background: Insects respond to the spatial and temporal dynamics of a pheromone plume, which implies not only a strong response to"odor on", but also to"odor off". This requires mechanisms geared toward a fast signal termination.
Rosell Pellisé, Glòria +25 more
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Structural Features of an OR37 Glomerulus: A Comparative Study
Frontiers in Neuroanatomy, 2017 In the olfactory bulb (OB) a sophisticated neuronal network mediates the primary processing of sensory information and extensive investigations over the past decades have greatly improved our understanding of the morphology and neuronal organization of ...
Anna-Maria Maier +2 more
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Computational investigation of aphid odorant receptor structure and binding function [PDF]
, 2022 Odorant receptors (OR) play a critical role in signal transduction and olfactory recognition in insects. Unfortunately, insect ORs are difficult to express and purify, and limited structural data are available.
Oldham, N. +14 more
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