Results 21 to 30 of about 2,668,755 (284)
Mammalian odorant receptor tuning breadth persists across distinct odorant panels. [PDF]
PLoS ONE, 2017 The molecular receptive range (MRR) of a mammalian odorant receptor (OR) is the set of odorant structures that activate the OR, while the distribution of these odorant structures across odor space is the tuning breadth of the OR.
Devin Kepchia +3 more
doaj +2 more sources
How Far Does a Receptor Influence Vibrational Properties of an Odorant? [PDF]
PLoS ONE, 2016 The biophysical mechanism of the sense of smell, or olfaction, is still highly debated. The mainstream explanation argues for a shape-based recognition of odorant molecules by olfactory receptors, while recent investigations suggest the primary olfactory
Anna Reese +3 more
doaj +3 more sources
Co-regulation of a large and rapidly evolving repertoire of odorant receptor genes [PDF]
BMC Neuroscience, 2007 The olfactory system meets niche- and species-specific demands by an accelerated evolution of its odorant receptor repertoires. In this review, we describe evolutionary processes that have shaped olfactory and vomeronasal receptor gene families in ...
Lane Robert P, Kambere Marijo B
doaj +2 more sources
Probing the optimal architecture and molecular mechanism of insect odorant receptor heteromeric channels [PDF]
Communications BiologyInsects have a powerful olfactory system that is far more selective and sensitive than artificial detectors. Insect odorant receptors (ORs) are key components of the system, which are ligand-gated ion channels comprising a specific odorant-sensing OR and
Wei Xue +7 more
doaj +2 more sources
Axonal Odorant Receptors Mediate Axon Targeting [PDF]
Cell Reports, 2019 Summary: In mammals, odorant receptors not only detect odors but also define the target in the olfactory bulb, where sensory neurons project to give rise to the sensory map.
Ilaria Zamparo +12 more
doaj +2 more sources
Elucidation of the structural basis for ligand binding and translocation in conserved insect odorant receptor co-receptors [PDF]
Nature Communications, 2023 In numerous insects, the olfactory receptor family forms a unique class of heteromeric cation channels. Recent progress in resolving the odorant receptor structures offers unprecedented opportunities for deciphering their molecular mechanisms of ligand ...
Jody Pacalon +6 more
doaj +2 more sources
BMC Genomics, 2019 Background Odorant receptor genes constitute the largest gene family in mammalian genomes and this family has been extensively studied in several species, but to date far less attention has been paid to the characterization of their mRNA 3′ untranslated ...
Mohamed Doulazmi +4 more
doaj +3 more sources
Insect Biochemistry and Molecular Biology, 2016 Olfaction is one of the main sensory modalities that allow insects to interpret their environment. Several proteins, including odorant-binding proteins (OBPs) and odorant receptors (ORs), are involved in this process.
Thiago A Franco +2 more
exaly +2 more sources
Odorant Receptor Sensitivity Modulation in Drosophila
Journal of Neuroscience, 2017 The ability to modulate sensitivity in sensory systems is essential for useful information to be extracted from fluctuating stimuli in a wide range of background conditions.
Hao Guo, Kishor Kunwar, Dean P. Smith
semanticscholar +2 more sources
Odorant receptor 7D4 activation dynamics
Angewandte Chemie, 2018 Deciphering how an odorant activates an odorant receptor (OR) and how changes in specific OR residues affect its responsiveness are central to understanding how we smell.
Claire A. de March +6 more
semanticscholar +2 more sources