Results 11 to 20 of about 1,252,084 (241)
Odorant Receptor Desensitization in Insects [PDF]
Journal of Experimental Neuroscience, 2017 Insects and other arthropods transmit devastating human diseases, and these vectors use chemical senses to target humans. Understanding how these animals detect, respond, and adapt to volatile odorants may lead to novel ways to disrupt host localization ...
Hao Guo, Dean P Smith
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The Mouse Solitary Odorant Receptor Gene Promoters as Models for the Study of Odorant Receptor Gene Choice. [PDF]
PLoS ONE, 2016 BACKGROUND:In vertebrates, several anatomical regions located within the nasal cavity mediate olfaction. Among these, the main olfactory epithelium detects most conventional odorants.
Andrea Degl'Innocenti +3 more
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Odorant and pheromone receptors in insects [PDF]
Frontiers in Cellular Neuroscience, 2009 Since the emergence of the first living cells, survival has hinged on the ability to detect and localize chemicals in the environment. Modern animal species ranging from insects to mammals express large odorant receptor repertoires to detect the ...
TAL S HA, Dean p Smith
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A conserved aspartic acid is important for agonist (VUAA1) and odorant/tuning receptor-dependent activation of the insect odorant co-receptor (Orco). [PDF]
PLoS ONE, 2013 Insect odorant receptors function as heteromeric odorant-gated cation channels comprising a conventional odorant-sensitive tuning receptor, and a conserved co-receptor (Orco).
Brijesh N Kumar +5 more
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Mammalian odorant receptor tuning breadth persists across distinct odorant panels. [PDF]
PLoS ONE, 2017 The molecular receptive range (MRR) of a mammalian odorant receptor (OR) is the set of odorant structures that activate the OR, while the distribution of these odorant structures across odor space is the tuning breadth of the OR.
Devin Kepchia +3 more
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OlfactionBase: a repository to explore odors, odorants, olfactory receptors and odorant–receptor interactions [PDF]
Nucleic Acids Research, 2021 Abstract Olfaction is a multi-stage process that initiates with the odorants entering the nose and terminates with the brain recognizing the odor associated with the odorant. In a very intricate way, the process incorporates various components functioning together and in synchronization.
Anju Sharma +3 more
openaire +3 more sources
An odorant receptor for a key odor constituent of ambergris. [PDF]
Commun BiolAmbergris, a substance derived from the digestive system of sperm whales, has been valued for centuries for its unique aromatic properties. However, historical accounts indicate that certain human populations, particularly in East Asia, utilized ambergris without regard for its odor quality.
Takase D +4 more
europepmc +4 more sources
Functional reconstitution of the insect odorant receptor co-receptor in a tethered lipid bilayer membrane [PDF]
, 2021 As membrane proteins are among the most important drug targets, it is critical to study membrane proteins to improve drug design. However, due to the myriad roles fulfilled by the cellular membrane, it is a highly complex environment and challenging to ...
Bernhard , Schuster +6 more
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BMB Reports, 2022 Odorant receptors (ORs), the largest subfamily of G protein-coupled receptors, detect odorants in the nose. In addition, ORs were recently shown to be expressed in many nonolfactory tissues and cells, indicating that these receptors have physiological and pathophysiological roles beyond olfaction.
Chan Chung +3 more
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Onset of Odorant Receptors [PDF]
Annals of the New York Academy of Sciences, 2009 Odorant receptors are thought to be critical determinants of olfactory sensory neuron axon targeting and organization. Nonetheless, a systematic characterization of the onset of odorant receptor expression has not yet been done in the main olfactory epithelium.
Diego J, Rodriguez-Gil +5 more
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