Results 141 to 150 of about 98,650 (241)
Myosin Inhibition in Non-obstructive Hypertrophic Cardiomyopathy: Lessons from ODYSSEY-HCM. [PDF]
Hasegawa K, Iguchi M, Wada H, Dan GA.
europepmc +1 more source
ABSTRACT Diabetes mellitus (DM) and chronic kidney disease (CKD) frequently coexist and together create a ‘triple threat’ with dyslipidaemia, enhancing the risk for cardiovascular morbidity and mortality. Diabetic kidney disease (DKD) leads to altered lipid metabolism through insulin resistance, inflammation and oxidative stress resulting in an ...
Ann S. Forrest +3 more
wiley +1 more source
How AI Is Speeding Up the Diagnostic Odyssey for Rare Diseases. [PDF]
Spichak S.
europepmc +1 more source
This book, Homer's Odyssey, was used by student Ida Mae Missildine, class of 1890, in her classes at Rollins College.
core
Long‐read sequencing‐based atlas of tissue‐specific expression of DNM1L transcript variants
Targeted long‐read sequencing resolves full‐length DNM1L (Drp1) isoforms and reveals conserved, tissue‐specific expression patterns across human and mouse tissues. Functional assays show that Drp1 isoforms differ in their ability to drive mitochondrial fission, independent of abundance, with specific exons modulating activity.
Feng Yan +19 more
wiley +1 more source
Dolutegravir as First- or Second-line Treatment for Children With HIV: 240-Week Follow-up of the ODYSSEY Randomized Trial. [PDF]
Mujuru HA +28 more
europepmc +1 more source
Astrocytic gap junctions formed by connexin43 (Cx43) help maintain brain homeostasis. After mild traumatic brain injury (TBI), total cortical Cx43 increases and redistributes toward a soluble, non‐junctional pool with elevated hemichannel activity and increased phosphorylation at serine 368 (pCx43S368).
Carmen Muñoz‐Ballester +11 more
wiley +1 more source
Efficacy and safety of alirocumab once-monthly in patients with atherosclerotic cardiovascular disease and without history of an acute atherothrombotic event. [PDF]
Tokgözöğlu L +10 more
europepmc +1 more source
The sorting nexin Snx21 promotes flotillin‐mediated endocytosis
In this study, we describe a novel function of the previously uncharacterized Snx21 protein as a specific positive regulator of flotillin‐mediated endocytic trafficking. Snx21 is recruited to endosomal membranes via binding to PI(3)P, and it colocalizes with flotillins on the surface of late endosomes.
Tamás Maruzs +9 more
wiley +1 more source

