Results 161 to 170 of about 224,855 (298)

The effects of cholesterol-lowering drugs on neurocognitive function: systematic review and meta analysis. [PDF]

Front Neurol
Li K, Li Y, Jiang X, Zhu Y.
europepmc   +1 more source

A neuroimmune odyssey [PDF]

Nature Reviews Immunology, 2020
openaire   +2 more sources

ZNF844 Suppresses Invasion and Metastasis in Nasopharyngeal Carcinoma by Inhibiting the PI3K‐AKT Signaling Pathway

Cancer Science, EarlyView.
ZNF844 functions as a tumor suppressor in NPC by inhibiting invasion and metastasis through regulation of the PI3K‐AKT signaling pathway. It may serve as a promising therapeutic target and prognostic biomarker for NPC. ABSTRACT Epigenetic regulation plays a crucial role in the development of nasopharyngeal carcinoma (NPC).
Jinping Xu, Cancan Chen, Bin Zhang, Shufang Liao, Yunyan Mo, Rongjun Zhang, Xiangyun Kong, Wei Jiang   +7 more
wiley   +1 more source

Dynamics of Apolipoprotein J Levels and Metabolic Parameters Following Bariatric Surgery

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Bariatric surgery has emerged as a potent intervention for ameliorating insulin resistance and its associated comorbidities in obese patients. Apolipoprotein J (ApoJ) and adiponectin are closely associated with insulin resistance and sensitivity, respectively.
Kellen Cristina da Cruz Rodrigues, Minjin Lee, Yejee Lim, Jennie Young, Brendon Chung, Susan Phillips, Theodore P. Ciaraldi, Young‐Bum Kim   +7 more
wiley   +1 more source

From the rare to the essential: analyzing the needs of physicians and families managing rare diseases. [PDF]

BMC Health Serv Res
Mussio I, Triunfo P, Gerstenblüth M, Raggio V, Cardozo P, Naya H, Spangenberg L.   +6 more
europepmc   +1 more source

How Has the Rise of Direct‐To‐Consumer Genetic Testing Impacted Genetic Counselling Practice? A Scoping Review

Clinical Genetics, EarlyView.
This scoping review consolidated research on genetic health practitioners' (GHPs) and direct to consumer genetic testing (DTC‐GT) consumer needs and identified gaps. Thematic analysis identified four domains: GHPs' views, GHPs' perceptions of the impact of DTC‐GT on consumers, how DTC‐GT impacted services and how DTC‐GT impacted roles.
Cushla McKinney, Giselle Newton, Vaishnavi Nathan, Aideen McInerney‐Leo   +3 more
wiley   +1 more source

From Stress Pathways to Space Biology: An Odyssey in Molecular and Translational Medicine. [PDF]

Biomedicines
Anastasiadi AT, Tzounakas VL.
europepmc   +1 more source

Whole Exome Sequencing for Romanian Patients With Neurodevelopmental Disorders Through an International Collaboration

Clinical Genetics, EarlyView.
Whole exome sequencing for Romanian patients with neurodevelopmental disorders through an international collaboration—this study has provided a 50% diagnostic yield for patients with NDDs (27 positive results from 54 patients), supporting the implementation of a WES analysis that can identify SNVs, small INDELs, CNVs, and mitochondrial variants ...
Alexandru Caramizaru, Cristina Durac, Andreea Dumitrescu, Alexandru Calota‐Dobrescu, Alix de Becdelièvre, Marina Konyukh, Denise Cassandrini, Hane Lee, Go Hun Seo, Seung Woo Ryu, Mihai Cucu, Iuliana Manuela Dragomir, Andreea Catana, Homa Tajsharghi, Edoardo Malfatti, Florin Burada, Amelia Dobrescu   +16 more
wiley   +1 more source

Which is the optimal choice in lipid-lowering therapy for reducing major cardiovascular events? a network meta-analysis. [PDF]

Front Pharmacol
Niu Q, Wang Q, Chen F, Li B.
europepmc   +1 more source

The Diagnostic Odyssey of a Biochemically Confirmed Case of ML II: The First Western Patient With LYSET Deficiency

Clinical Genetics, EarlyView.
We identify a female patient with a homozygous nonsense variant (p.Gln38Ter) in the LYSET gene. This is the first western report of a challenging case of an extensive diagnostic odyssey and demonstrates that the LYSET gene must be considered in the differential diagnosis when M6P‐labeled lysosomal enzymes are altered.
Fernanda Sperb‐Ludwig, Taciane Alegra, Leonardo Martinello da Rosa, Nataniel Floriano Ludwig, Renata Voltolini Velho, Ida Vanessa Doederlein Schwartz   +5 more
wiley   +1 more source