The FEBS Journal, EarlyView.Here, we report the role of extracellular vesicles (EVs) released from melanoma cells constitutively expressing MHC class II in the regulation of immune cell functions and melanoma metastasis. In particular, we observed an increased localization of HLA‐DRα, CAM receptors, PD‐L1, and STAT3 signaling proteins in the EVs.
Francesca Costantini +4 more
wiley +1 more source
Widespread Verrucous Plaques of Chromoblastomycosis: A 12-Year Diagnostic Odyssey. [PDF]
Clin Case RepShrestha E +3 more
europepmc +1 more source
Enhancing the Evidence for Care in Underserved Bleeding Disorders Communities
Haemophilia, EarlyView.ABSTRACT Background Major advances in haemophilia care have not translated equitably across all populations. Individuals with rare bleeding disorders (RBDs), people living in low‐ and lower‐middle‐income countries (LMICs) and women and girls with inherited bleeding disorders (WGWBD) continue to face significant diagnostic, therapeutic and research ...
Johnny Mahlangu
wiley +1 more source
Type 2 MI a legitimate efficacy endpoint in cardiovascular trials? A critical appraisal. [PDF]
Front Cardiovasc Medvan Bruggen FH, Luijendijk HJ.
europepmc +1 more source
The Illness Narratives of Children and Young People With Spinal Muscular Atrophy: A Scoping Review
Journal of Advanced Nursing, EarlyView.ABSTRACT Aim(s) This review seeks to explore the illness narratives of children and young people focusing on their healthcare trajectories; the right to health; and the kind of stories told about them. Design This scoping review adopts a narrative approach to analyse how the illness experience of Spinal Muscular Atrophy is represented in the literature,
Marcela González‐Agüero +6 more
wiley +1 more source
Incidence of P200 pemphigoid: A nationwide study
Journal of the European Academy of Dermatology and Venereology, EarlyView.The anti‐LAMB4 cell‐based immunoassay is a new serological technique that is far superior to dermal immunoblotting for detecting autoantibodies directed against the P200 protein. This method allows a re‐evaluation of the incidence of P200 pemphigoid, which appears to be considerably more frequent than epidermolysis bullosa acquisita.
Fabienne Jouen +7 more
wiley +1 more source
Chronic <i>Mycobacterium kansasii</i> Pleural Infection Mimicking Metastatic Breast Cancer: A Seven-Year Diagnostic Odyssey and the Critical Role of Metagenomic Sequencing. [PDF]
Infect Drug ResistFang T, Hu P, Zhang Y, Hu B, Miao Q.
europepmc +1 more source
Erythrocyte ‘Feierzeit’ reaction: Novel filamentous and vesicular response to n‐butyl acetate
Journal of Microscopy, EarlyView.Abstract Human erythrocytes (red blood cells; RBCs) undergo spontaneous disassembly after several hours of exposure to n‐butyl acetate (nBA). Images of the morphological changes were captured in time‐lapse sequences using differential interference contrast (DIC) light microscopy.
Philip W. Kuchel
wiley +1 more source
Evaluating the potential effect of PCSK9 inhibitors on the risk of sudden cardiac death and ventricular arrhythmias: A meta-analysis of randomized controlled trials. [PDF]
PLoS OneZhang L, Li YY, Liu XH, Liu HJ, Xu Q.
europepmc +1 more source
Petrography and mineral chemistry of Northeast Africa 053—A remnant of Martian crystal mush
Meteoritics &Planetary Science, EarlyView.Abstract In Earth's igneous systems, crystal mushes, crystal‐rich frameworks permeated by silicate melt, represent a common and fundamental stage in the evolution of magma bodies. However, whether crystal mushes occur within Martian igneous systems and play a comparable role is unknown. Here, we present a comprehensive petrography and mineral chemistry
Xhonatan Shehaj +2 more
wiley +1 more source