Results 191 to 200 of about 224,855 (298)

The Hemoprotein Hhy1 Promotes Heme‐Dependent Catalase Activity of Ctt1

open access: yesMolecular Microbiology, EarlyView.
A Schizosaccharomyces pombe strain deficient in heme (hem1Δ) and siderophore (Fc) biosynthesis, as well as high‐affinity iron (Fe) uptake (blue), was used to uncover the hemoprotein Hhy1 that promotes the heme‐dependent activity of the catalase Ctt1. In contrast, hhy1Δ cells exhibit reduced Ctt1 activity and increased sensitivity to oxidative stress ...
Tobias Vahsen   +3 more
wiley   +1 more source

Anticipation of a therapeutic odyssey following predictive testing for autism. [PDF]

open access: yesSci Rep
MacDuffie KE   +13 more
europepmc   +1 more source

Alleviation of photoaging‐associated MMP upregulation, prostanoid biosynthesis, and cell cycle arrest with titanium dioxide, zinc oxide, and inorganic‐only (ZnO + TiO2) sunscreens

open access: yesPhotochemistry and Photobiology, EarlyView.
Inorganic sunscreens containing the UV filters titanium dioxide (TiO2) and/or zinc oxide (ZnO) alleviated various biomarkers of photoaging in human dermal fibroblasts, at a gene and protein level. The study provides novel insights that observe the impact of inorganic photoprotection through the molecular biology of skin.
Neil Dominic T. Pangilinan   +4 more
wiley   +1 more source

The role of constitutive nitric‐oxide synthase in regulation of IKKα after ultraviolet irradiation

open access: yesPhotochemistry and Photobiology, EarlyView.
cNOS enhances IKKα expression following UVB exposure by promoting promoter activation, transcriptional elongation, and Ets‐1 stabilization. These actions sustain IKKα levels, reduce UV‐induced skin carcinogenesis, and highlight cNOS as a key protective factor against solar UV damage.
Yuxi Zhou   +6 more
wiley   +1 more source

PCSK9 targeting therapies for familial hypercholesterolaemia: a meta-analysis of efficacy on lipid biomarkers and safety in adults and children across 23 RCTs. [PDF]

open access: yesOpen Heart
Ho VQT   +11 more
europepmc   +1 more source

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