Results 221 to 230 of about 1,900,133 (252)

Impact of geographical location on ICU outcomes in adults: a scoping review. [PDF]

open access: yesBMJ Open
Zand J   +7 more
europepmc   +1 more source

Development of a Zebrafish Embryo‐Based Test System for Thyroid Hormone System Disruption: 3Rs in Ecotoxicological Research

open access: yesEnvironmental Toxicology and Chemistry, EarlyView.
Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz   +9 more
wiley   +1 more source

Inconsistent Transcriptomic Responses to Hexabromocyclododecane in Japanese Quail: A Comparative Analysis of Results From Four Different Study Designs

open access: yesEnvironmental Toxicology and Chemistry, EarlyView.
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers   +10 more
wiley   +1 more source

New approach methodologies for next-generation risk assessment of nanomaterials and nano-enabled products. [PDF]

open access: yesNano Converg
Lee E   +39 more
europepmc   +1 more source

Effects of Lactic Acid Bacteria and Yeasts on Growth Performance, Intestinal Health, and Organ Morphometry of Broiler Chickens

open access: yesFood Safety and Health, EarlyView.
The fermentation of molasses‐vinasse with lactic acid bacteria and yeasts improves growth, intestinal health, digestive, and immune organs in chickens, promoting their productive performance and organic development. ABSTRACT This study evaluated the probiotic effects of lactic acid bacteria and yeasts on productive parameters, intestinal health, and ...
José Miranda‐Yuquilema   +4 more
wiley   +1 more source

Safety and Metabolic Effects of Withania somnifera Seed Extract and Powder in Rats: Insights From DPP‐4 Molecular Docking

open access: yesFood Safety and Health, EarlyView.
Withania somnifera seed extract and powder improved metabolic parameters in rats, particularly at higher extract doses, without evident hepatic, renal, hematological, or histopathological toxicity. Molecular docking further predicted strong DPP‐4 inhibitory potential of withanone, supporting the antidiabetic potential of W. somnifera seeds.
Muhammad Usman Khalid   +8 more
wiley   +1 more source

Beyond political risk: Toward a holistic understanding of multinational enterprise resilience in the era of cascading crises

open access: yesGlobal Strategy Journal, EarlyView.
Abstract Research Summary This article develops a conceptual framework for understanding multinational enterprise (MNE) resilience in the era of cascading crises. We define resilience as the MNE's capacity to absorb disruption, maintain or restore functioning, and reconfigure operations as conditions shift.
Gerard George, Chang Hoon Oh
wiley   +1 more source

Political Economy of Budgeting Reforms: A Comparative Analysis of the Adoption and Implementation of Programme‐Based Budgeting in Health Across Seven LMIC Countries

open access: yesThe International Journal of Health Planning and Management, EarlyView.
ABSTRACT Despite its widespread application in public financial management reforms across low‐ and middle‐income countries, programme‐based budgeting (PBB) implementation often remains relatively superficial. The technical weaknesses of the reform have been widely documented; however, the political economy dynamics around the introduction and ...
Maria Paola Bertone   +5 more
wiley   +1 more source

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