OECD workshop consensus report: Ethical considerations with respect to human derived products, specifically human serum, in OECD test guidelines [PDF]
Frontiers in Toxicology, 2023 The ethical needs and concerns with use and sourcing of human materials, particularly serum, in OECD in vitro test guidelines were explored in a dedicated international workshop held in 2019.
Miriam N. Jacobs +15 more
doaj +2 more sources
Developing OECD test guidelines for regulatory testing of nanomaterials to ensure mutual acceptance of test data [PDF]
Regulatory Toxicology and Pharmacology, 2019 The OECD Working Party on Manufactured Nanomaterials (WPMN) provides a global forum for discussion of nano-safety issues. Together with the OECD Test Guidelines Programme (TGP) the WPMN has explored the need for adaptation of some of the existing OECD Test Guidelines (TGs) and Guidance Documents (GDs) as well as developing new TGs and GDs to ...
Peter Kearns +2 more
exaly +4 more sources
History of the Organisation for Economic Co-operation and Development (OECD) test guidelines for non-animal test methods in Japan [PDF]
Genes and EnvironmentThe number of alternatives to animal tests (non-animal test methods) for human health developed globally account for more than 40% of the test methods in the Organisation for Economic Co-operation and Development (OECD) Guidelines for the Testing of ...
Hajime Kojima
doaj +2 more sources
An In vitro assessment of the genotoxic potential of short-, medium-, and long-chain triacylglycerides [PDF]
Frontiers in ToxicologyThe genotoxic potential of a mixture of short-, medium-, and long-chain triacylglycerides (SMLCT), a novel synthetic fat intended as a non-animal alternative for food applications, was evaluated using a standard battery of in vitro assays in accordance ...
Sydney Schreppler +5 more
doaj +2 more sources
Towards test guidelines and standards for advanced materials: scientific insights and recommendations from the MACRAMÉ project [PDF]
Frontiers in ToxicologyThe Horizon Europe Project MACRAMÉ developed twelve recommendations towards Test Guidelines and Standards for safety assessment of advanced materials (AdMas) that capture the identified needs in characterisation and identification, safety testing ...
Anna Pohl +21 more
doaj +2 more sources
From concept to regulation: OECD’s role in the development of the DNT in vitro battery [PDF]
Frontiers in ToxicologyChemical exposure during critical stages of nervous system development can lead to adverse neurotoxic effects, known as developmental neurotoxicity (DNT).
Magdalini Sachana +2 more
doaj +2 more sources
Assessments of the impact of metals on juvenile earthworms (Eisenia fetida) in laboratory conditions [PDF]
Kragujevac Journal of Science, 2022 The aim of this study was to evaluate the impact of different concentrations of copper and zinc on the mortality and bodyweight of juvenile earthworms in artificial soil.
Sekulić Jovana M. +4 more
doaj +1 more source
Animals, 2022 The OECD test guidelines for animal experiments play an important role in evaluating the chemical hazards. Animal tests performed using OECD guidelines, especially when the good laboratory practice (GLP) principle is applied, reduce the duplication of ...
Yong Hyun Chung +3 more
doaj +1 more source
Comparative study on genotoxicity methods between OECD Test guidelines and GB15193
Zhongguo shipin weisheng zazhi, 2022 ObjectiveThe purpose of this study is to compare genotoxicity methods between OECD test guidelines and China food safety standards（GB15193）．MethodsMain parameters of related genotoxicity methods in OECD Testing Guidelines and GB 15193 standards were ...
ZHANG Xiaopeng +3 more
doaj +1 more source
In vitro prediction of clinical signs of respiratory toxicity in rats following inhalation exposure
Current Research in Toxicology, 2021 To date there are no OECD validated alternative approaches to study toxicity following inhalation exposure to airborne chemicals. The available OECD test guidelines for acute inhalation toxicity aim to estimate a value of the lethal air concentration of ...
E. Da Silva +4 more
doaj +1 more source