Results 31 to 40 of about 18,586 (163)

A 2024 inventory of test methods relevant to thyroid hormone system disruption for human health and environmental regulatory hazard assessment [version 1; peer review: 2 approved]

Open Research Europe
Thyroid hormone system disruption (THSD) is a growing concern in chemical hazard assessment due to its impact on human and environmental health and the scarce methods available for assessing the THSD potential of chemicals.
Lola Bajard, Lucia Vergauwen, Ingrid Langezaal, Sabrina Tait, Alessandra Roncaglioni, Anita Sosnowska, Ann-Cathrin Haigis, Annick D van den Brand, Klára Hilscherová, Ellen Hessel, Jiří Novák, Nafsika Papaioannou, Natalia Buławska, Eliana Spilioti, Elisavet Renieri, Arno C Gutleb, Anastasia Spyropoulou, Dimitra Nikolopoulou, Henrik Holbech, Dries Knapen, Miriam N Jacobs   +20 more
doaj   +1 more source

The OECD expert meeting on ecotoxicology and environmental fate — Towards the development of improved OECD guidelines for the testing of nanomaterials

Science of The Total Environment, 2014
On behalf of the OECD Working Party on Manufactured Nanomaterials (WPMN) an expert meeting on ecotoxicology and environmental fate of nanomaterials (NMs) took place in January 2013 in Berlin. At this meeting experts from science, industry and regulatory bodies discussed the applicability of OECD test guidelines (TGs) for chemicals to nanomaterials. The
Kühnel, Dana, Nickel, Carmen
openaire   +2 more sources

Limitations and Modifications of Skin Sensitization NAMs for Testing Inorganic Nanomaterials

Toxics
Since 2020, the REACh regulation requires toxicological data on nanoforms of materials, including the assessment of their skin-sensitizing properties.
Britta Wareing, Ayse Aktalay Hippchen, Susanne N. Kolle, Barbara Birk, Dorothee Funk-Weyer, Robert Landsiedel   +5 more
doaj   +1 more source

Synthesis of Surfactants Derived from 2-Mercaptobenzimidazole and Study of Their Acute Toxicity and Analgesic and Psychotropic Activities

Biochemistry Research International, 2019
The aim of the present study is to synthesize cationic salts from a relatively toxic compound named 2-mercaptobenzimidazole and to evaluate some of their pharmacological properties.
Terence Nguema Ongone, Latyfa El Ouasif, Mostafa El Ghoul, Redouane Achour, Hind Chakchak, Meryem El Jemli, Yahia Cherrah, Katim Alaoui, Amina Zellou   +8 more
doaj   +1 more source

Applicability of the OECD Test Guideline 201 to graphene-related materials: Dispersion stability matters

Ecotoxicology and Environmental Safety
Graphene-related materials (GRMs) are used in many innovative applications for their outstanding physico-chemical properties. Their possible release could have critical consequences for the environment.
Giada Caorsi, Fabio Candotto Carniel, Morgan Légnani, Emmanuel Flahaut, Viviana Jehová González, Ester Vázquez, Maurizio Prato, Mauro Tretiach   +7 more
doaj   +1 more source

Feasibility of assessing vegetative and generative endpoints of crop- and non- crop terrestrial plant species for non-target terrestrial plant (NTTP) regulatory testing under greenhouse conditions.

PLoS ONE, 2020
Agriculture is the dominating land-use in the EU member states covering nearly half of the surface area. Using herbicides to reduce weed competition in agricultural areas can adversely affect Non-Target Terrestrial Plants (NTTP) growing in field margins.
Andreas Duffner, Thomas Moser, Marco P Candolfi   +2 more
doaj   +1 more source

Microbial biopesticides are inhibited by honey bee royal jelly and in vitro larval diet

Environmental Sciences Europe
The interest in and use of biological materials in crop production is increasing globally at a rapid pace. In many cases, testing methods for conventional chemicals are applied to microbial-based biopesticides because specific microbial test methods are ...
Daniel R. Schmehl, David Larsen, Camille Gomez, Lisa Ortego   +3 more
doaj   +1 more source

Development of RT h-CLAT, a Rapid Assessment Method for Skin Sensitizers Using THP-1 Cells as a Biosensor

Biosensors
In recent years, in vitro skin sensitization assays have been recommended as animal-free alternatives for the safety assessment of cosmetics and topical drugs, and these methods have been adopted in OECD test guidelines.
Hiroki Koyama, Ayami Maeda, Peiqi Zhai, Keiichiro Koiwai, Kouichi Kurose   +4 more
doaj   +1 more source

Under Review: Data Requirements and Method Development of a New Bee Risk Assessment Scheme for Plant Protection Product Registration

CHIMIA, 2020
An up-to-date ecotoxicological risk assessment of plant protection products (PPPs) depends on the constant improvement of risk assessment methods and guidelines, and a thorough evaluation of their impacts. Here, we explain how the risk assessment of PPPs
Lukas Jeker, Daniela Grossar
doaj   +1 more source

Acute Oral Toxicity, Histopathological Analysis, and Antimalarial Potential of Jatropha tanjorensis Leaf Extracts [PDF]

Asia Pacific Journal of Medical Toxicology
Background: Jatropha tanjorensis is a leafy vegetable widely consumed across Africa and is valued in folk medicine for its reputed blood-replenishing properties.
Fatima Jumare, Helen Ileigo Inabo, Muhammad Hassan Isa Doko, Gbonjubola Olusesan Adeshina   +3 more
doaj   +1 more source