Results 101 to 110 of about 300 (123)

Inhibition of 5α-Reductase and Aromatase by the Ellagitannins Oenothein A and Oenothein B fromEpilobiumSpecies

Planta Medica, 1997
Species of the genus Epilobium (Onagraceae) have been investigated for their activity against 5 alpha-reductase and aromatase, two enzymes which are involved in the aetiology of benign prostatic hyperplasia (BPH). Activity-guided fractionation has led to the identification of two macrocyclic ellagitannins, oenothein A (1) and oenothein B (2), as the ...
Ducrey B, Marston A, Göhring S, Hartmann RW, Hostettmann K   +4 more
openaire   +3 more sources

Stimulation and priming of innate lymphocytes by oenothein B (89.59)

The Journal of Immunology, 2010
Abstract Oenothein B is an immunomodulatory tannin isolated from the Epilobium angustifolium plant. This compound is known to affect myeloid cells and these effects include enhanced chemotaxis, NF-κB activation, and production of proinflammatory cytokines, including TNFα and IL-6. Its effects on other innate immune cells have not been
Andrew Ramstead, Igor Schepetkin, Mark Quinn, Mark Jutila   +3 more
openaire   +1 more source

Oenothein B, dimeric hydrolysable tannin inhibiting HCV invasion from Oenothera erythrosepala

Journal of Natural Medicines, 2018
The envelope proteins of the hepatitis C virus (HCV), E1 and E2, have been revealed to be essential for invasion of HCV. Thus, we were engaged in the search for the inhibitors against HCV invasion through the assay system using the model virus expressing recombinant HCV envelopes, E1 and E2. Now, we disclosed dimeric hydrolysable tannin oenothein B (1)
Satoru Tamura, Gang-Ming Yang, Teruaki Koitabashi, Yoshiharu Matsuura, Yasumasa Komoda, Tomikazu Kawano, Nobutoshi Murakami   +6 more
openaire   +2 more sources

Regulatory Effect and Mechanism of Oenothein B in Reducing Fat Accumulation in Caenorhabditis Elegans

European Journal of Lipid Science and Technology, 2023
AbstractOenothein B (OEB) displays various biological activities, including immunomodulatory, antioxidant, and anticancer effects. However, the underlying mechanisms remain unclear. Therefore, in this study, the effect of OEB isolated from Eucalyptus leaves on fat deposition and its underlying mechanism are explored in Caenorhabditis elegans （C.elegans)
Xiaoying Zhang, Qiaoxing Liu, Yun Chen, Wei Li, Konglong Feng, Jie Xiao, Yong Cao, Zuanxian Su, Guang Wang, Yunjiao Chen   +9 more
openaire   +1 more source

Content of oenothein B in willow herb depending on growing conditions

2022
Introduction. Chamerion angustifolium (L.) Holub (Onagraceae) is a representative of willow herb species found throughout lower temperate northern regions. Its use to treat prostatic adenoma has been reported. Willow herb has been traditionally used in folk medicine and currently it is a potential raw material for the production of phytopharmaceuticals.
Uminska, Kateryna, Ivanauskas, Liudas, Kozurak, Alla, Georgiyants, Victoriya, Mykhailenko, Olha   +4 more
openaire   +1 more source

Investigation on the inactivation of trypsin by oenothein B: isothermal titration calorimetry and docking studies

International Journal of Food Science & Technology, 2019
SummaryThe aim of this study was to investigate the inhibitory mechanism of oenothein B (OeB), a unique oligomer ellagitannin with a rigid structure, on porcine trypsin using fluorescence spectroscopy, isothermal titration calorimetry (ITC), circular dichroism (CD) and molecular docking.
Li Wang, Huijun Liang, Zitao Liu, Jingfeng Zhang, Yu Wang, Jian Xiao, Lichao Zhao   +6 more
openaire   +1 more source

In vitro cytotoxic activity of Cuphea ingrata Cham. & Schltdl. extracts related to the oenothein B content

Natural Product Research, 2023
Agnieszka Galanty, Danuta Sobolewska, Monika Olszewska   +2 more
exaly  

Oenothein B inhibits human non-small cell lung cancer A549 cell proliferation by ROS-mediated PI3K/Akt/NF-κB signaling pathway

Chemico-Biological Interactions, 2019
Lihe Jiang, Yumeng Zhang, Xiaodong Pei   +2 more
exaly  

Variation in concentration of oenothein B in different samples of cultivated Epilobium angustifolium L

Planta Medica, 2008
AN Shikov, ON Pozharitskaya, SA Ivanova, VG Makarov, VP Tikhonov, B Galambosi   +5 more
openaire   +1 more source

Immunological Effects of Oenothein B, an Ellagitannin Dimer, on Dendritic Cells

International Journal of Molecular Sciences, 2013
Takashi Yoshida, Morio Yoshimura, Yoshiaki Amakura   +2 more
exaly