Results 51 to 60 of about 443,504 (230)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Research on Taking off and Landing Separation of Aircrafts in Airport Category Ⅱ Operation
工程科学与技术, 2019 In order to estimate the change trend of aircraft taking off and landing separation in case of low visibility, improve the efficiency of runway use and reduce flight delay, an aircraft taking off and landing separation model in airport category Ⅱ ...
Kai YANG, Rui KANG
doaj
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
A Transformer-Based Dual-Mode Ka-Band CMOS Power Amplifier With Enhanced Back-Off Efficiency
IEEE Journal of MicrowavesThis paper presents the differential-to-single-ended load-modulated (DISEL)-power amplifier, a transformer-based dual-mode Ka-band CMOS power amplifier designed to enhance power-added efficiency (PAE) under output back-off conditions while maintaining ...
Hyunsoo Kim, Jaeyong Lee, Changkun Park
doaj +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Off-Chip Memory Allocation for Neural Processing Units
IEEE AccessMany modern Systems-on-Chip (SoCs) are equipped with specialized Machine Learning (ML) accelerators that use both on-chip and off-chip memory to execute neural networks.
Andrey Kvochko +4 more
doaj +1 more source
MATEC Web of Conferences, 2018 Traffic performance have been measured based on degree of saturation, velocity, travel time, and delays. However, they weren’t enough to measure the traffic fluctuation that happen on normal days.
Hartanto Susilo Budi, Imanuel Ivan
doaj +1 more source