Results 51 to 60 of about 7,149,350 (256)

Off-site Manufacture in Australia : Current State and Future Directions [PDF]

open access: yes, 2007
Off-site manufacture (OSM) offers numerous benefits to all parties in the construction process. The\ud uptake of OSM in Australia has, however, been limited. This limited uptake corresponds to similar trends\ud in the UK and US, although the level of OSM

core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

The Development of a BIM-Based Interoperable Toolkit for Efficient Renovation in Buildings: From BIM to Digital Twin

open access: yesBuildings, 2022
Nowadays, buildings renovation is a subject of special interest since the building and construction sector is the main body responsible for energy consumption and emissions.
Bruno Daniotti   +10 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Contractor Perceptions of Off-Site Modular Construction in Kuwait: An Investigation of Current Practices

open access: yesEngineering Proceedings
Kuwait faces a pressing challenge in expanding its existing buildings to meet growing demands. The rising popularity of modular construction systems, with their off-site construction approach, offers promising solutions. In this research, we explored the
Areej AlBanwan   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Stakeholder Mapping and Analysis of Off-Site Construction Projects: Utilizing a Power–Interest Matrix and the Fuzzy Logic Theory

open access: yesBuildings
Stakeholder management is a crucial component in the implementation of off-site construction (OSC) projects, while stakeholder mapping serves as a practical technique to facilitate an in-depth understanding of different project stakeholders.
Qing Zhu   +5 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Optimization Models for Reducing Off-Cuts of Raw Materials in Construction Site

open access: yesMathematics, 2022
More than ten billion tons of construction waste are generated every year in the world. The large volume of construction waste not only increases costs for contractors, but also poses a threat to the environment.
Haoqing Wang, Wen Yi
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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