Results 61 to 70 of about 1,357,177 (300)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Stakeholder Mapping and Analysis of Off-Site Construction Projects: Utilizing a Power–Interest Matrix and the Fuzzy Logic Theory

Buildings
Stakeholder management is a crucial component in the implementation of off-site construction (OSC) projects, while stakeholder mapping serves as a practical technique to facilitate an in-depth understanding of different project stakeholders.
Qing Zhu, Jiade Xi, Xin Hu, Heap-Yih Chong, Yijun Zhou, Sainan Lyu   +5 more
doaj   +1 more source

Optimization Models for Reducing Off-Cuts of Raw Materials in Construction Site

Mathematics, 2022
More than ten billion tons of construction waste are generated every year in the world. The large volume of construction waste not only increases costs for contractors, but also poses a threat to the environment.
Haoqing Wang, Wen Yi
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Drivers constraints and the future of off-site manufacture in Australia. [PDF]

, 2007
Much has been written on Off-site Manufacture (OSM) in construction, particularly regarding the perceived benefits and barriers to implementation. However, very little understanding of the state of OSM in the Australian construction industry exists. A ‘
Blismas, Nick, Wakefield, Ron
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Design Analysis of Mass Timber and Volumetric Modular Strategies as Counterproposals for an Existing Reinforced Concrete Hotel

Buildings
Construction professionals work in silos and use traditional design and construction methods. The growing demand for rapidly built and high-quality construction is making off-site manufacturing mainstream.
Marie-Laure Filion, Sylvain Ménard, Carlo Carbone, Mohamad Bader Eddin   +3 more
doaj   +1 more source

"Off-piste pedagogy" : construction site visits for undergraduate civil engineers [PDF]

, 2016
Undertaking construction site visits with undergraduate civil engineers can assist students to acclimatise to the realities of construction contracting practice.
Murray, Michael, Tennant, Stuart
core  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source