Results 91 to 100 of about 3,882,147 (309)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Small corrections ... Dec. [19]43. Preliminary chartDepths shown by bathymetric isolines and soundings.; Includes notes, tidal and conversion tables, list of conspicuous objects and 1 inset map: Bathurst.; "Preliminary chart" -- at head of title ...
Great Britain. Hydrographic Office;
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Büro çalışma alanlarının geliştirilmesi önerildiğinde çok sık olarak akla gelen; “verimlilik üzerinde ne gibi etkiler bekleyebiliriz?” sorusudur. Yöneticiler ya da işverenler, büro tasarımı için yapılan yatırımların, kurumsal verimlilik ile ilgili ...
Mehmet Altınöz, Ramazan Göral
doaj
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
News from the Office of Research
September 1, 2016: September research workshops -- Deadline for WSU research grants is Oct.7 -- Intellectual property management workshop -- WSU announces request for proposals for interdisciplinary cluster hire -- T3 moves to Research and Technology ...
Office of Research
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TAMUG Office of Public Information, 1962-2008 [PDF]
Office Records. Includes In The News, press releases, office correspondence, cruises and a small number of Summer WAVES.
TAMUG Office of Public Information
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
A Report on the Office of Censorship
Report discussing the United States Office of Censorship during World War II. It discusses the Office director's view of censorship; postal, cable, press, and radio censorship; and the achievements of censorship during the ...
United States. Office of Censorship
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